Anything 3D modeling related not covered by Blender, and software for 3D printing, just as an example. The word "still" in your post suggests you expect F/OSS

Anything 3D modeling related not covered by Blender, and software for 3D printing, just as an example. The word "still" in your post suggests you expect F/OSS software to eventually become available for all fields of application. But that's not what I see happening; instead, there's no new desktop (as opposed to cloud) software being released at all, much less on Linux. So Wine is here to stay with us to (increasingly) run old Win software out of maintenance, and works surprisingly well. Of course, that's made possible by Win32 itself having excellent binary compatibility in the first place, as opposed to the Linux user land.