Yes especially when you consider things that aren't places. Science Fiction being a big one. There's Santa Fe, CDMX though. You may have decided that Santa Fe

Yes especially when you consider things that aren't places. Science Fiction being a big one. There's Santa Fe, CDMX though. You may have decided that Santa Fe, NM is too small, but you may not have considered that one. People don't normally call that SF though - but they could. And that's why SF ought to have a more narrow use than SFO.