The other aspect of twilight sedations is: do you feel pain and then lose the conscious memory, but retain the stress reaction's affect on your body? And simil

The other aspect of twilight sedations is: do you feel pain and then lose the conscious memory, but retain the stress reaction's affect on your body? And similarly for anesthesia: even if you don't feel pain, is your body having a stress reaction? Obviously yes to some extent, for the non-neural pathways that are physically insulted during the procedure, but what about for neural pathways?