Nowadays you don't need to mess with Wine manually, there are a lot of tools to install Windows binaries just like they were Linux binary. You'll even forget yo

Nowadays you don't need to mess with Wine manually, there are a lot of tools to install Windows binaries just like they were Linux binary. You'll even forget you're using Windows versions. You can check ProtonDB for compatibility. The information is valid even if you have the GOG version of the game. For games that are not on Steam there is WineDB but I find that the UI isn't as nice as ProtonDB. Steam has a Linux launcher and let you install Windows binaries directly. For GOG or Epic games there is Heroic launcher which is very easy to use. Don't overthink your distribution choice, just go for one of the major general purpose distribution (Ubuntu, Fedora, Mint, etc) and you'll be fine no matter what you pick.