3 ms·

Don't we already have a vaccine for HPV?

toomuchtodo 4y ago
We do, but uptake is not great in the US versus other developed countries [1]. There are efforts to improve this [2]. Australia’s high uptake rate is leading to possible eradication of cervical cancer by 2035 [3]. Tangentially, there is substantial evidence viruses lead to various cancers, and with vaccines being such high leverage wrt cost:value, we should be leaning hard into prevention (although mRNA and CRISPR will still be necessary paths for cancer treatment). [1] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6482788/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6482788/ [2] http://hpvroundtable.org/wp-content/uploads/2019/09/05_School_Entry_Requirements_for_HPV_Vaccination_WEB_updated.pdf http://hpvroundtable.org/wp-content/uploads/2019/09/05_Schoo... [3] https://www.theguardian.com/australia-news/2023/feb/02/australia-on-track-to-eliminate-cervical-cancer-by-2035-amid-rising-hpv-vaccination-rates https://www.theguardian.com/australia-news/2023/feb/02/austr...
- yjftsjthsd-h 4y ago
  > but uptake is not great in the US versus other developed countries It's painfully confounded with other variables, but that could provide a (noisy) quick check on how likely it is that HPV causes the cancer increase, right? If there's an effective vaccine with varied uptake, then we should be able to compare countries by rate of vaccination and cancer, and see if there's a substantial negative correlation.
drdec 4y ago
Yes - unfortunately uptake is limited as some people see giving your child the vaccine as a green light for sexual activity.
- pengaru 4y ago
  Those same people don't educate their children on the existence of HPV and its role in their future diseases. The kids have already been green-lit in this department via total ignorance of the risks. Uptake is limited simply because it hasn't been required in the USA as part of school enrollment. This is the primary driver of vaccination in the country. I'm fairly certain you're conflating hormonal birth control with HPV vaccination.
  - drdec 4y ago
    > I'm fairly certain you're conflating hormonal birth control with HPV vaccination. No, I'm talking about HPV vaccination. It comes up every so often in parent forums and there are always people taking this position. Not that it doesn't happen with respect to birth control as well.

We do, but uptake is not great in the US versus other developed countries [1]. There are efforts to improve this [2]. Australia’s high uptake rate is leading to possible eradication of cervical cancer by 2035 [3]. Tangentially, there is substantial evidence viruses lead to various cancers, and with vaccines being such high leverage wrt cost:value, we should be leaning hard into prevention (although mRNA and CRISPR will still be necessary paths for cancer treatment). [1] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6482788/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6482788/ [2] http://hpvroundtable.org/wp-content/uploads/2019/09/05_School_Entry_Requirements_for_HPV_Vaccination_WEB_updated.pdf http://hpvroundtable.org/wp-content/uploads/2019/09/05_Schoo... [3] https://www.theguardian.com/australia-news/2023/feb/02/australia-on-track-to-eliminate-cervical-cancer-by-2035-amid-rising-hpv-vaccination-rates https://www.theguardian.com/australia-news/2023/feb/02/austr...

yjftsjthsd-h 4y ago
> but uptake is not great in the US versus other developed countries It's painfully confounded with other variables, but that could provide a (noisy) quick check on how likely it is that HPV causes the cancer increase, right? If there's an effective vaccine with varied uptake, then we should be able to compare countries by rate of vaccination and cancer, and see if there's a substantial negative correlation.

drdec 4y ago

Yes - unfortunately uptake is limited as some people see giving your child the vaccine as a green light for sexual activity.

pengaru 4y ago
Those same people don't educate their children on the existence of HPV and its role in their future diseases. The kids have already been green-lit in this department via total ignorance of the risks. Uptake is limited simply because it hasn't been required in the USA as part of school enrollment. This is the primary driver of vaccination in the country. I'm fairly certain you're conflating hormonal birth control with HPV vaccination.
- drdec 4y ago
  > I'm fairly certain you're conflating hormonal birth control with HPV vaccination. No, I'm talking about HPV vaccination. It comes up every so often in parent forums and there are always people taking this position. Not that it doesn't happen with respect to birth control as well.