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> Reading DNA in vitro I think the most promising method is DNA nanopore tech (http://en.wikipedia.org/wiki/Nanopore_sequencing http://en.wikipedia.org/wiki/Na
by michaelgrosner 15y ago
> Reading DNA in vitro
I think the most promising method is DNA nanopore tech (http://en.wikipedia.org/wiki/Nanopore_sequencing http://en.wikipedia.org/wiki/Nanopore_sequencing). It doesn't require labeling, amplification, and, I suppose, could be done in vitro. Maybe that's what the article is referring to?
I'm not 100% sure on this, but it also may be much more accurate than current methods since it doens't suffer from many of the biases present in current next-gen sequencers.
I'm working on my PhD in computational biophysics and this is truly an exciting time to be doing cutting edge bio-stuff like this. Sometimes I think people will look back on the 2010's and say this was like Silicon Valley in the 70s and 80s... the beginning of something big.