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If this is safer and as efficacious as DNP it will be a net health benefit. The other drug which manipulates mitochondria to promote weight loss is DNP (2,4-Di
by runnerup 4y ago
If this is safer and as efficacious as DNP it will be a net health benefit.
The other drug which manipulates mitochondria to promote weight loss is DNP (2,4-Dinitrophenol). That works by collapsing the proton motive force that the cell uses to produce most of its ATP chemical energy. Instead of producing ATP, the energy of the proton gradient is lost as heat.
Thus, it’s very easy to overdose on DNP and die by overheating. Your body just creates “infinite” heat uncontrollably until you die.
“Drug” is a term used loosely with DNP: In 1938, the FDA included DNP in a list of drugs potentially so toxic that they should not be used even under a physician's supervision. It’s no longer prescribed anywhere but lives on in niche personal usage for some bodybuilders and atheletes.
It’s primarily an explosive, actually!
- TeaBrain 4y agoLearned about DNP from the Peter Attia podcast. As I recall, it was discovered in part due to factory workers who worked with DNP losing significant amounts of weight.