4 ms·
I've been curious about these so called immortal cell lines. Do they really just mean by immortal something qualitative and at the extremes, like some unreasona
by jxramos 4y ago
I've been curious about these so called immortal cell lines. Do they really just mean by immortal something qualitative and at the extremes, like some unreasonably high number of cell division cycles before senescence takes over and the tissue reaches end of line? I've been curious if anyone's ever sequenced the DNA from these lines to see if they're truly the same source organism or have diverged or another organism was slipped in their place unbeknownst to anyone not looking.
- whatshisface 4y agoMost immortal lines come from samples of tumors. I don't know how GOOD Meat is doing it.
- zkms 4y agoThey claim to use the spontaneously immortalized UMNSAH/DF-1 chicken fibroblast cell line, which isn't a tumor cell line. I still wouldn't eat any "cultured meat" regardless of the cell line (if my great-grandparents didn't eat it, I'm not eating it) but there is a difference between immortalized and full-on cancerous cells.
- fbdab103 4y ago>I've been curious if anyone's ever sequenced the DNA from these lines to see if they're truly the same source organism or have diverged or another organism was slipped in their place unbeknownst to anyone not looking. Cellline contamination is a real problem where a foreign population out competes the intended cell line. There are estimates that thousands of papers have been published where the intended cellline has been accidentally replaced with HeLa.