That would depend very much on your publisher... that could be anywhere from "use this page size and send a PDF" to "manuscripts only and our designer/typesette

That would depend very much on your publisher... that could be anywhere from "use this page size and send a PDF" to "manuscripts only and our designer/typesetter/etc. will work on the rest". As someone who has used CSS in the way described here, I think it's beneficial even if you end up having to redo it in InDesign. It may not be a perfect 1:1 but simply coming up with the rules will make setting up styles and master pages in publishing software much more straightforward.