3 ms·
> The purpose of our study was to evaluate the impact of short-term high-caloric feeding and fasting on bone microarchitecture. We hypothesized that both high-c
by gnicholas 4y ago
> The purpose of our study was to evaluate the impact of short-term high-caloric feeding and fasting on bone microarchitecture. We hypothesized that both high-caloric feeding and fasting would have negative effects on microarchitecture.
I know it shouldn't have a huge impact on my assessment of a study, but when I see that they were looking for not-x and found x, it makes me feel substantially more confident in the result. It only guarantees that they were not p-hacking, and doesn't have any bearing on other aspects that would affect the validity of the results.
- franciscop 4y agoI came to the comments first assuming there'd be p-hacking (a broad amount of parameters would be tested trying to find some that have "statistical significance", which is bogus and commonly referred as p-hacking). I am a bit tired of seeing very promising articles, becoming hopeful then just to read HN comments on why it's ridiculously flawed (I do get HN tends to be negative, but in scientific articles in a good way, I prefer no-results that fake positive hopes). Very happy to see your comment and I def agree, if looking for specifically not-x and found x it also increases my trust in an article A LOT.