3 ms·

oh yea i think i have some family on wegovy ( or maybe mounjaro now ), hadn't realized that it was approved for obesity. What i don't understand is that you ar

oh yea i think i have some family on wegovy ( or maybe mounjaro now ), hadn't realized that it was approved for obesity. What i don't understand is that you are saying these are "preventative treatments for obesity" . aren't preventative treatements given before the condition even comes into picture, these drugs are after you get obese so not sure how they are preventative. Doesn't weight just come back instantly once you stop these drugs. Hard time accepting that solution is putting 200million americans on this drug for rest of their lives. "Cardiometabolic improvements seen from week 0 to week 68 with semaglutide reverted towards baseline at week 120 for most variables." https://dom-pubs.onlinelibrary.wiley.com/doi/10.1111/dom.14725 https://dom-pubs.onlinelibrary.wiley.com/doi/10.1111/dom.147...

tristor 4y ago
I didn't say it prevents obesity, I said it prevents Type 2 Diabetes, which is a chronic disease caused by obesity. And it does. It's nearly a miracle drug. Yes, if you stop taking the drugs, after a short time you return exactly how you were prior. You must take these drugs for life, unless something else comes out that improves the situation.
- dangwhy 4y ago
  > it prevents Type 2 Diabetes Ah I understand now what you meant. I remember looking into while ago( i have like half my extended family on these drugs now lol) but couldn't really find evidence to support this claim. "There is only limited-quality evidence that at-risk patients taking GLP-1 receptor agonists are less likely to progress to diabetes (number needed to treat [NNT] = 23). Serious adverse events were more likely in patients taking GLP-1 receptor agonists than in patients taking placebo (number needed to harm [NNH] = 42). There is insufficient evidence to evaluate the effect of DPP-4 inhibitors on at-risk patients. There is no evidence that either medication class affects the development of diabetes-associated complications.1" https://www.aafp.org/pubs/afp/issues/2018/0401/p437.html https://www.aafp.org/pubs/afp/issues/2018/0401/p437.html

tristor 4y ago

I didn't say it prevents obesity, I said it prevents Type 2 Diabetes, which is a chronic disease caused by obesity. And it does. It's nearly a miracle drug. Yes, if you stop taking the drugs, after a short time you return exactly how you were prior. You must take these drugs for life, unless something else comes out that improves the situation.

dangwhy 4y ago
> it prevents Type 2 Diabetes Ah I understand now what you meant. I remember looking into while ago( i have like half my extended family on these drugs now lol) but couldn't really find evidence to support this claim. "There is only limited-quality evidence that at-risk patients taking GLP-1 receptor agonists are less likely to progress to diabetes (number needed to treat [NNT] = 23). Serious adverse events were more likely in patients taking GLP-1 receptor agonists than in patients taking placebo (number needed to harm [NNH] = 42). There is insufficient evidence to evaluate the effect of DPP-4 inhibitors on at-risk patients. There is no evidence that either medication class affects the development of diabetes-associated complications.1" https://www.aafp.org/pubs/afp/issues/2018/0401/p437.html https://www.aafp.org/pubs/afp/issues/2018/0401/p437.html