3 ms·
Long Covid is real. If you don't think it's real, you're either completely nontechnical in biology or just have been out of the loop and are regurgitating garba
by Madmallard 4y ago
Long Covid is real. If you don't think it's real, you're either completely nontechnical in biology or just have been out of the loop and are regurgitating garbage you're spreading around that makes you feel better about not being sick or something. I don't know the reason, but it's harmful as fuck to society regardless.
Whether it be astroturfing or other means originally founded by pharmaceutical companies knowing they originally did not test drugs for mitochondrial toxicity prior to Phase 1 trials, the source remains to be seen. It's also possible they just weren't aware of the problems before they became problems. Heterogeneous damage to cellular respiration does not generally become apparent until it's obvious for example in really old people.
The fact is that people are by and large developing metabolic dysfunction earlier on, and things like antibiotics drastically accelerate the problem. Bactericidal antibiotics are widely known in research now to be seriously toxic to mitochondria and the damage they cause leads to chronic processes because mitochondria do not have effective repair mechanisms outside of copies. When they start reproducing mutated copies, the person does not get off scot-free anymore. Processed foods and air pollution and chemical exposures from foods and other things all additionally cause more dysregulation. This is all becoming way more widely known.
Some percentage of people will just not bounce back after these insults. Respiratory viruses and bacterial infections induce a large amount of oxidative stress in the human body, largely caused by your own immune system. Normally, your body has redox mechanisms to balance this out so you are fine in the end (otherwise running would cause a lot of problems really quickly!). But combining our toxic environment, toxic antibiotics that most people take (and many women take bactericidal antibiotics for UTIs!), high processed food diets leading to excessive baseline OS, you potentiate the risk for the individuals own mitochondrial machinery to be severely damaged from a high OS insult. After that, you don't bounce back. You develop chronic fatigue and severe exercise intolerance, and have much more precarious relationships with other illnesses.
This is what's happening. Depression other mental disorders are already strongly associated with metabolic dysregulation in research.
Don't blame the victims. It's likely you'll become one yourself before you're very old. Everyone is getting sicker.