I wonder if these differences in effect might have to do with the emergence, and wider adoption, of abuse-deterrent formulations of drugs? Case in point; https

I wonder if these differences in effect might have to do with the emergence, and wider adoption, of abuse-deterrent formulations of drugs? Case in point; https://www.fiercepharma.com/pharma/vallons-abuse-resistant-adderall-fails-clinical-trial-causing-stock-crater https://www.fiercepharma.com/pharma/vallons-abuse-resistant-...