4 ms·
Some clarification: the stereoisomers of amphetamine found in Adderall are levoamphetamine and dextroamphetamine, the former feels "speedier" because it mostly
by sph 4y ago
Some clarification: the stereoisomers of amphetamine found in Adderall are levoamphetamine and dextroamphetamine, the former feels "speedier" because it mostly affects the body (heart rate, blood pressure, fight-or-flight response) whereas the latter mostly affects the brain (wakefulness, focus, etc.) Adderall exists because apparently a small amount of levoamphetamine has been shown to produce some effect on focus, but most of the heavy lifting is done by the right-handed isomer. In my opinion the risk of addiction is higher if there is a noticeable physical high.
Which is why I personally have decided to go with dextroamphetamine (in the long release form of lisdexamphetamine) which doesn't cause any body stimulation, and in fact lowers my blood pressure due to reduced anxiety, while producing no physical stimulation whatsoever. A cup of coffee feels "stronger" than lisdex.
In Britain Ritalin (methylphenidate) is usually first line treatment for children, while Elvanse (lisdexamfetamine) is preferred in adults. AFAIK Adderall is not prescribed here.
- capitainenemo 4y agoThe wakefulness thing has been offered as a theory for the doubled rate of psychosis in ADHD children on Adderall compared to Ritalin. https://www.healthline.com/health/adhd/adderall-psychosis https://www.healthline.com/health/adhd/adderall-psychosis https://www.nejm.org/doi/full/10.1056/NEJMoa1813751 https://www.nejm.org/doi/full/10.1056/NEJMoa1813751 "Studies of Adderall and similar stimulants, such as methylphenidate (Ritalin), estimate that psychosis occurs in about 0.10 percent of users. However, new research with over 300,000 adolescents with ADHD showed that the rates of psychosis in adolescents in the amphetamine group was as high as 0.21 percent. "
- nibbleshifter 4y ago> AFAIK Adderall is not prescribed here. It is, depends on the psych really. I know a good few in the UK on dex, or amp salts, or whatever.