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Right, but that's the thing... some of these drugs might work for some and kill other people unexpectedly. The efficacy for one person doesn't mean that it woul
by tibbon 15y ago
Right, but that's the thing... some of these drugs might work for some and kill other people unexpectedly. The efficacy for one person doesn't mean that it wouldn't kill every other person that takes it, and looking at a sample size of 1 (nobel laureate or not) doesn't make for good science or good medicine.
- beedogs 15y agoSome people who have exhausted all other treatment options might opt for it even then, though. At least they can.
- Dn_Ab 15y agoThis is exactly why personalized medicine, bioinformatics, computational pharmacokinetics, etc is key for the future of medicine. I am not a biologist but I imagine someday soon a scenario like this will be possible: You have a model of the sites and interactions the drug targets, and optimum biology - metabolism, target cells' proteomes etc. Measure these in the patient and you can predict ahead of time the efficacy of the drug and then optimize the drug's chemistry to be more effective for this individual. With a better understanding of protein modelling and such you could do a search for similar structures and compute the expected interactions and optimize for personalized effectiveness.