3 ms·
The longer duration and fat solubility of canabinoids makes the alcohol comparison difficult. Many people have a glass of red wine with dinner daily, and are no
by clbrmbr 4y ago
The longer duration and fat solubility of canabinoids makes the alcohol comparison difficult. Many people have a glass of red wine with dinner daily, and are not drunk in the daytime, but even very light cannabis consumption nightly seems to result in a permanent low-level stonnedness.
- gaganyaan 4y agoDo you have a source for permanent low level stonedness? TBH that sounds completely made up.
- clbrmbr 4y agoI did not intend that as an empirical observation but rather a mathematical pharmacokinetic result of fat-solubility rather than water-solubility. THC is fat-soluble and so has a higher volume of distribution which drives a longer half-life. (See Shulgin “The Nature of Drugs” pg 132) And “constant” would be a better word than “permanent”, as certainly it should go away after some weeks of abstinence.
- deleted 4y ago[deleted]