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There is no cure for hearing damage. Your body can recover from slight damage after a few weeks but generally trauma to hair cells, synapses and auditory nerve

There is no cure for hearing damage. Your body can recover from slight damage after a few weeks but generally trauma to hair cells, synapses and auditory nerve is accumulative and overtime they loose their ability to recover. There's currently no way to regenerate these. There was a promising company attempting to do this and they recently announced discontinuation of phase 3 trials as their drug showed no significant change against placebo. The drug was in development for almost 9 years before it reached phase 3 and failed.

llanowarelves 4y ago
Thanks for that update, I heard about it only once years ago. Yeah safest thing is to assume it can't come back, and be aware of the accumulation, as you said.
torstenvl 4y ago
> There is no cure for hearing damage. There's no silver-bullet cure for hearing damage, but there are cures and effective treatment for the underlying causes, which can result in a cure for hearing damage. The treatment and prognosis is highly dependent on the underlying cause. Cilia damage probably won't be curable until after a lot more stem cell research. Neurological damage is hard to impossible to cure depending on the age and neuroplasticity of the patient. TMJ or Eustachian tube dysfunction can lead to hearing damage that goes away once the underlying issue is treated. This misinformation has killed people. Texas Roadhouse CEO Kent Taylor committed suicide after being diagnosed with tinnitus and being told it was untreatable, even though his tinnitus was caused by a COVID-19 infection causing inflammation. The treatment for that, which is highly effective, is two weeks of prednisone, with intratympanic steroid injections in severe cases.
- deleted 4y ago
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- EatShitHN 4y ago
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AnthonBerg 4y ago
In my experience and according to literature, there are cures for hearing damage. N-acetylcysteine, for one. I had been taking N-acetylcysteine (NAC) regularly for a while for reasons completely unrelated to hearing. I unmistakably noticed my hearing to improve. High frequency hearing once lost came back. I didn’t believe it. Looked on Google Scholar. The effect is known. The literature supports it; here’s just one paper: https://www.frontiersin.org/articles/10.3389/fcell.2021.659486/full https://www.frontiersin.org/articles/10.3389/fcell.2021.6594... Antioxidant properties seem to be what’s helping, and I’d guess it’s the mucolytic aspect of NAC as well.
- CommanderData 4y ago
  There may be cures in future (ways to regenerate all the areas that are involved in hearing - Auditory nerve, synapse and OHC, IHC) but there currently is no way to regenerate HC after apoptosis in Humans. Recovery of damaged/stressed HC, auditory is shown to happen naturally to a degree and -might- be helped through supplements. I take NAC myself and a few other supplements, the idea is to help support and lessen the effects of oxidative stress. I wouldn't promote any of my protocol since the literature is too weak and from various hearing related forums I read, efficacy highly subjective. If you're wondering - 7,8 Dihydroxyflavone (DHF) shows promise and there's some literature on frontiersin on this but delivery was done intratympanic injection to the RWM and on animals. Taking the it as a oral supplement may raise risks of some cancers.
  - AnthonBerg 4y ago
    Thanks! Yes, it’s important to distinguish between cure-some-types-somewhat-sometimes and cure-almost-any-type-consistently. I’ve been very surprised in recent years to learn just how much actionable information is in the scientific literature. More is known than is known, sort of.
  - makk 4y ago
    Sounds like you've looked into this. Understand you wouldn't promote your protocol but I'd like to learn about it. How can I reach you?

llanowarelves 4y ago

Thanks for that update, I heard about it only once years ago. Yeah safest thing is to assume it can't come back, and be aware of the accumulation, as you said.

torstenvl 4y ago

> There is no cure for hearing damage. There's no silver-bullet cure for hearing damage, but there are cures and effective treatment for the underlying causes, which can result in a cure for hearing damage. The treatment and prognosis is highly dependent on the underlying cause. Cilia damage probably won't be curable until after a lot more stem cell research. Neurological damage is hard to impossible to cure depending on the age and neuroplasticity of the patient. TMJ or Eustachian tube dysfunction can lead to hearing damage that goes away once the underlying issue is treated. This misinformation has killed people. Texas Roadhouse CEO Kent Taylor committed suicide after being diagnosed with tinnitus and being told it was untreatable, even though his tinnitus was caused by a COVID-19 infection causing inflammation. The treatment for that, which is highly effective, is two weeks of prednisone, with intratympanic steroid injections in severe cases.

deleted 4y ago
[deleted]
EatShitHN 4y ago
[dead]

AnthonBerg 4y ago

In my experience and according to literature, there are cures for hearing damage. N-acetylcysteine, for one. I had been taking N-acetylcysteine (NAC) regularly for a while for reasons completely unrelated to hearing. I unmistakably noticed my hearing to improve. High frequency hearing once lost came back. I didn’t believe it. Looked on Google Scholar. The effect is known. The literature supports it; here’s just one paper: https://www.frontiersin.org/articles/10.3389/fcell.2021.659486/full https://www.frontiersin.org/articles/10.3389/fcell.2021.6594... Antioxidant properties seem to be what’s helping, and I’d guess it’s the mucolytic aspect of NAC as well.

CommanderData 4y ago
There may be cures in future (ways to regenerate all the areas that are involved in hearing - Auditory nerve, synapse and OHC, IHC) but there currently is no way to regenerate HC after apoptosis in Humans. Recovery of damaged/stressed HC, auditory is shown to happen naturally to a degree and -might- be helped through supplements. I take NAC myself and a few other supplements, the idea is to help support and lessen the effects of oxidative stress. I wouldn't promote any of my protocol since the literature is too weak and from various hearing related forums I read, efficacy highly subjective. If you're wondering - 7,8 Dihydroxyflavone (DHF) shows promise and there's some literature on frontiersin on this but delivery was done intratympanic injection to the RWM and on animals. Taking the it as a oral supplement may raise risks of some cancers.
- AnthonBerg 4y ago
  Thanks! Yes, it’s important to distinguish between cure-some-types-somewhat-sometimes and cure-almost-any-type-consistently. I’ve been very surprised in recent years to learn just how much actionable information is in the scientific literature. More is known than is known, sort of.
- makk 4y ago
  Sounds like you've looked into this. Understand you wouldn't promote your protocol but I'd like to learn about it. How can I reach you?