Perpetual happiness is already a solved problem in humans. It's called the mu-opioid receptor. That's what opioid junkies sprawled on the sidewalk half-naked

Perpetual happiness is already a solved problem in humans. It's called the mu-opioid receptor. That's what opioid junkies sprawled on the sidewalk half-naked in San Francisco have discovered. Fentanyl is very cheap and you could put someone in factory farm like confines and feed them bare sustenance and fentanyl for the rest of their lives and they'd probably be "happy" if kept perpetually high. However, those opioid receptors should not be pushed synthetically because they have been positioned by evolution in all sorts of strategic spots to encourage pro-social behavior, mating, eating, etc. that are part of our millions year old evolutionary program that must have intrinsic value in itself. If it has no intrinsic value and any happiness is as good as any other happiness, then someone spending the rest of their lives in an opioid haze and someone interacting with the world in a way that evolution tells them to in order to be happy would be considered equivalent, and that would be the end of the human race essentially.