This raised the question for me of how long could we sustain this before the loss of mass to the moon started to affect earth? 22 billion tons a year seems mass

This raised the question for me of how long could we sustain this before the loss of mass to the moon started to affect earth? 22 billion tons a year seems massive but doing that for 100 years would only decrease the moon's mass by 2.2e-11 which seems completely insignificant (not that I would know what is insignificant here) and if we had not solved the problem in 100 years we probably have bigger issues anyways. How long could such a thing be maintained before we had to start thinking about the new problem that we were creating? Working at the astronomical scale has never been a strong point for me.