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I understand that cancer drugs can be used for other things. That makes perfect sense to me. But we are not talking about using cancer drugs for things other th

I understand that cancer drugs can be used for other things. That makes perfect sense to me. But we are not talking about using cancer drugs for things other than cancer in general, we're talking about using them as puberty blockers. The use of estrogen-blocking drugs as puberty blockers is not a good idea just because estrogen blocking drugs exist. They were not originally intended for that.

jemmyw 4y ago
> They were not originally intended for that. Why is this important? Lots of things find use outside their original purpose. Intent doesn't really matter over function.
- FluentFlan 4y ago
  To be clear, I was not saying or imply GnRH agonists are estrogen blockers. Or making any claims about GnRH, it's uses or history of use. Or saying tamoxifen would be a good for use a puberty blocker. I was simply making the point that a drugs origin does not automatically imply something about the safety or the plausibility of it's use in other areas. I in fact agree with everything rhinoceraptor has said about puberty blockers. It's not new or anything to be panicked about. This non-issue is be used extremely transparently to stoke a "won't you think of the children" moral panic where trans people and trans kids are being made the punching bags. I'm old enough to remember when essentially all the same talking points were being used to drum up a moral panics about gay/lesbian folks. (I'm not even that old) That is why I called it rhetoric. I believe the poster I was responding to (RobotToaster) and it seems JoeyBananas are attempting to conflate puberty blockers (and if you read between the lines: trans people) with cancer. It's purpose is not to convey information but to inspire feelings, feelings of fear and unease. Of course I can't know the posters hearts and I have met folks who genuinely didn't understand the litany of dog whistles and red flags they were shooting off. It very lame to see yet another well known person (ŽIžek) jump in on it.
- JoeyBananas 4y ago
  It suggests using these drugs as puberty blockers is a "wildcat" application that is not widely accepted
  - FluentFlan 4y ago
    You need to substantiate your claim that off label use is even occuring. But before you get to that: "These drugs" - what drugs? You've not even demonstrated that you know what drugs are being used as puberty blockers in the UK.
rhinoceraptor 4y ago
GnRH agonists are not estrogen blockers. And they have decades of history in use for children as puberty blockers, for reasons that have nothing to do with gender, early puberty.

jemmyw 4y ago

> They were not originally intended for that. Why is this important? Lots of things find use outside their original purpose. Intent doesn't really matter over function.

FluentFlan 4y ago
To be clear, I was not saying or imply GnRH agonists are estrogen blockers. Or making any claims about GnRH, it's uses or history of use. Or saying tamoxifen would be a good for use a puberty blocker. I was simply making the point that a drugs origin does not automatically imply something about the safety or the plausibility of it's use in other areas. I in fact agree with everything rhinoceraptor has said about puberty blockers. It's not new or anything to be panicked about. This non-issue is be used extremely transparently to stoke a "won't you think of the children" moral panic where trans people and trans kids are being made the punching bags. I'm old enough to remember when essentially all the same talking points were being used to drum up a moral panics about gay/lesbian folks. (I'm not even that old) That is why I called it rhetoric. I believe the poster I was responding to (RobotToaster) and it seems JoeyBananas are attempting to conflate puberty blockers (and if you read between the lines: trans people) with cancer. It's purpose is not to convey information but to inspire feelings, feelings of fear and unease. Of course I can't know the posters hearts and I have met folks who genuinely didn't understand the litany of dog whistles and red flags they were shooting off. It very lame to see yet another well known person (ŽIžek) jump in on it.
JoeyBananas 4y ago
It suggests using these drugs as puberty blockers is a "wildcat" application that is not widely accepted
- FluentFlan 4y ago
  You need to substantiate your claim that off label use is even occuring. But before you get to that: "These drugs" - what drugs? You've not even demonstrated that you know what drugs are being used as puberty blockers in the UK.

rhinoceraptor 4y ago

GnRH agonists are not estrogen blockers. And they have decades of history in use for children as puberty blockers, for reasons that have nothing to do with gender, early puberty.