4 ms·
...in mice.
by loa_in_ 4y ago
...in mice.
- whatshisface 4y agoIt already does end the inflammation in mice, it could end it in humans.
- rzzzt 4y agoIs there a study on how many discoveries made on animal models could be turned into practical treatment for human subjects (percentage-wise)? I can't find one easily.
- doctor_eval 4y agoFor MS the number of treatments that made it to the clinic is depressingly low, however (a) that's changed recently, and (b) in this case it's a new pathway. So maybe this is interesting.
- atombender 4y agoThe problem is that mice can't get MS. When researchers experiment on mice, they do so using animal models. With MS these models are Experimental Autoimmune Encephalomyelitis (EAE) and Theiler’s Murine Encephalitis Virus-Induced Demyelinating Disease (TMEV-IDD). Neither is MS. So if you cure a mouse with EAE, you've cured them of EAE, not MS, and there's no knowing if the same treatment works on MS in humans.
- devin 4y agoOne way of knowing is, y’know, trying.
- xkcd-sucks 4y agoAnd that's how all the Alzheimer's drugs that do absolutely nothing get approved :)
- tomrod 4y ago> The problem is that mice can't get MS. Correct. Why do you think mice with EAE are a reference in the research of MS?
- Broken_Hippo 4y agoSure, but that's what folks say about all of the mice studies. Any of them could end x in humans. Most mice studies don't go further.