3 ms·
“Lean mass loss was 2.6% versus 10.9%. Those on tirzepatide had about a threefold greater reduction in fat mass than lean mass, resulting in an overall improvem
by aantix 4y ago
“Lean mass loss was 2.6% versus 10.9%. Those on tirzepatide had about a threefold greater reduction in fat mass than lean mass, resulting in an overall improvement in body composition. Fat mass as a proportion of overall body mass decreased from 46.8% to 44.7% with placebo, compared with 46.2% to 38.5% with tirzepatide. Similarly, lean mass as a proportion of body mass increased from 50.7% to 52.4% with placebo, compared with 51.0% to 58.1% with tirzepatide. Fat-to-lean mass ratio improved more with tirzepatide than placebo, with greater improvements observed in patients who lost more body weight.”
https://www.practiceupdate.com/content/easd-2022-substantial-weight-reduction-with-tirzepatide-produces-multiple-beneficial-metabolic-effects/142614#:~:text=Those%20on%20tirzepatide%20had%20about,%25%20to%2038.5%25%20with%20tirzepatide https://www.practiceupdate.com/content/easd-2022-substantial....
- exfatloss 4y agoYea, their overall composition still improved of course, because they lost more than 50% in fat. But they lost more lean mass than people who lose that weight in other ways, is my understanding.