3 ms·
They are also doing studies on human neutrophil cells etc. at 80 uM. The fluid above the cells at 80 uM is a model for cells in blood. You can see in Figure 5
by Mistletoe 4y ago
They are also doing studies on human neutrophil cells etc. at 80 uM. The fluid above the cells at 80 uM is a model for cells in blood.
You can see in Figure 5 here that the effects are really only seen at the highest non physiological doses. Even their lowest dose of GenX is 2.6 uM which is 2600 nM. I don’t have data for blood levels of GenX but if it is like PFOA that would be 260x higher than any concentration we would expect a neutrophil to ever see. And there is no effect on respiratory burst.
https://www.tandfonline.com/doi/epdf/10.1080/1547691X.2023.2176953?needAccess=true&role=button https://www.tandfonline.com/doi/epdf/10.1080/1547691X.2023.2...