Afaik, having worked in HPC, one area where this can be employed is error bias correction of CFD models. E.g. weather models have various biases that need to be

Afaik, having worked in HPC, one area where this can be employed is error bias correction of CFD models. E.g. weather models have various biases that need to be corrected for - so far this is just done with some relatively simple statistics afaik.