I'm not sure what part of my comment you're responding to because I wasn't referring to anything related to backwards compatibility. I was responding to the oth

I'm not sure what part of my comment you're responding to because I wasn't referring to anything related to backwards compatibility. I was responding to the other commenter asserting that biotech companies have somehow made an incorrect judgement call by purchasing certain types of instrument. In reality these vendors assume you're going to keep the system air-gapped forever, some don't even (officially) support joining their control PCs to a domain. Anecdotally I've found that in a lot of cases unless you're dealing with strange custom drivers usually the vendor-provided PCs can be replaced with new computers running the same control software (sometimes in compatibility mode if needed) and still operate the instrument.