4 ms·
That’s pretty much unreadable to someone not in the field. I’ve read it three times and still don’t know the answer to the GPs question. Yes I might be stupid,
by thejohnconway 4y ago
That’s pretty much unreadable to someone not in the field. I’ve read it three times and still don’t know the answer to the GPs question. Yes I might be stupid, but I do have a biology degree.
- idontwantthis 4y agoIt sounds to me like they tried to make really easy to mutate bacteria develop resistance and failed to do so.
- aflag 4y agoMore to it, from a layperson's point of view, that paragraph seems to contradict the headline. As they seemed to find COER mutants, albeit in low quantities, which I read as bacteria that could actually resist it? Maybe they are saying that even though there are some bacteria that can resist it, they are never actually selected? But what would the mechanism for that be?
- someguydave 4y agothey recovered “low-level COER” mutants, maybe they can’t reproduce? Edit: oh MIC is “minimum inhibitory concentration” so they only saw survivors with low levels of antibiotic. Still, it seems reasonable to be skeptical, just because their tests did not find resistance does not prove it will never happen
- aflag 4y agoI'm not skeptical or unskeptical. I just don't understand. My guess is that there's no construction if you understand what they are saying.