Links have previously been made in multiple studies between the use of anti-microbial mouthwash and increased mortality risk. One hypothesis is that it disrupt

Links have previously been made in multiple studies between the use of anti-microbial mouthwash and increased mortality risk. One hypothesis is that it disrupts the nitrate-nitrite-nitric acid pathway as the below linked review article goes into details on. Use of anti-bacterial mouthwash has also been linked to blood pressure rises, possible explained by the same mechanism. Antiseptic mouthwash, the nitrate–nitrite–nitric oxide pathway, and hospital mortality: a hypothesis generating review: https://link.springer.com/article/10.1007/s00134-020-06276-z https://link.springer.com/article/10.1007/s00134-020-06276-z Over-the-counter mouthwash use, nitric oxide and hypertension risk: https://pubmed.ncbi.nlm.nih.gov/31709856/ https://pubmed.ncbi.nlm.nih.gov/31709856/