It really depends on what you want to build. For typical web applications (e.g. SaaS) this stack is almost perfect: Next.js for client- and server-side develop

It really depends on what you want to build. For typical web applications (e.g. SaaS) this stack is almost perfect: Next.js for client- and server-side development (alternatively look at Remix). It's a big advantage to use Typescript on both sides instead of mixing programming languages like JS + Rust or GO (or PHP, Python, Ruby ...). In case you need a database (MySQL or Postgres) then PrismaORM is your best friend. Amazingly good ORM which does all the heavy-lifting for you. For hosting without database Vercel is the obvious solution. In case you need a database, then look at a good PaaS like Render.com (or if you are in EU then scalingo.com). In any case don't waste time with building infrastructure. In case you want to see a full application, check out our open-source Kickstarter. Repo: https://github.com/roqtech/roq-kickstarter-nextjs https://github.com/roqtech/roq-kickstarter-nextjs Demo: https://roq-kickstarter-nextjs.vercel.app/ https://roq-kickstarter-nextjs.vercel.app/ Repo (with Prisma): https://github.com/roqtech/roq-kickstarter-nextjs-prisma-marketplace https://github.com/roqtech/roq-kickstarter-nextjs-prisma-mar...