Regarding security, my advice is to always have two bags. The main bag has all your clothes, toiletries, etc. All the stuff you would be sad but not devastate

Regarding security, my advice is to always have two bags. The main bag has all your clothes, toiletries, etc. All the stuff you would be sad but not devastated to lose. In the other, smaller bag goes the Macbook, camera, and everything else that would be terrible to lose. Also, consider thin dry bags (I think mine are Sea to Summit) to keep out moisture and sand, two things which are inevitable on any adventure. :-) Having toted an SLR everywhere, I'll admit that unless you're an avid photographer, you will probably be happier and less anxious with a quality point-and-shoot. I gave an awful lot of impromptu classes on photography to people with SLRs that had kit lenses (not much better than a good P&S) and wildly inappropriate settings (much worse than a P&S).