3 ms·
With more As you risk running into the upper limit on sequence length for the virus shell and with less you run the risk of quicker degradation and not enough e
by kevviiinn 4y ago
With more As you risk running into the upper limit on sequence length for the virus shell and with less you run the risk of quicker degradation and not enough expression
- subroutine 4y agoThe first point being only a concern if you are a virus. If instead you are engineering say, an rna vaccine, you could package your transcript into lipofectamine instead of a coronavirus envelope ;) but point taken, there's always an upper limit.
- kevviiinn 4y agoAlso a concern when engineering viruses for research or other treatments such as the AAVs
- subroutine 4y agoTrue. I should have said "if you are using a virus"