Mitochondria need Manganese Super Oxide Dismutase (MnSOD) to mitigate the harmful effects of free radicals/reactive oxygen species (ROS). Manganese (Mn) and Ir

Mitochondria need Manganese Super Oxide Dismutase (MnSOD) to mitigate the harmful effects of free radicals/reactive oxygen species (ROS). Manganese (Mn) and Iron (Fe) share the same gut transporters and other transporters in the body (Divalent Metal Transporter). Fe based ROS generate the most heat in our bodies, which is why we tend not to feel the cold when young, but do when we age. When looking at the risks of too much manganese like Parkinson's, I wonder if, when we are born, are our Mn levels so high our baby/toddler/child like lack of coordination is due to excess amounts of Mn in the body? Main risks of excess Mn is from non ingested routes into the body, like inhalation and injection including perinatal (food) drips in hospitals of all places!!! Mn also does alot more in the body besides becoming MnSOD, so is this study actually witnessing the effects of not enough Manganese in the diet? The Mediterranean diet is high in seafood. Coastal waters have the highest concentration of Manganese which is why I would use mussels for my source of Omega-3 over deep sea fish, because the mussels will have a higher concentration of Manganese than the deep sea fish. Some studies suggest glycine can increase the lifespan/duration of mitochondria, so are these immune system responses like the one mentioned here an indication of an incomplete or unbalanced diet?