3 ms·

The effect of high-polyphenol Mediterranean diet on visceral adiposity

33 points by lxm 4y ago

FollowingTheDao 4y ago
Very much to do with the Polyphenols inhibiting or increasing Nitric Oxide Synthase. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3524723/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3524723/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2723458/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2723458/ https://academic.oup.com/eurheartj/article/24/13/1210/397048 https://academic.oup.com/eurheartj/article/24/13/1210/397048 Myself, I cannot drink green tea or eat chocolate because it inhibits NOS1 and I have a genetic sensitivity (NOS1AP) that causes them to trigger mania, anxiety, and insomnia as do many of the phenols in many plant foods. https://onlinelibrary.wiley.com/doi/10.1111/gbb.12193 https://onlinelibrary.wiley.com/doi/10.1111/gbb.12193
- readingnews 4y ago
  >> Myself, I cannot drink green tea or eat chocolate because it inhibits NOS1 and I have a genetic sensitivity (NOS1AP) that causes them to trigger mania, anxiety, and insomnia as do many of the phenols in many plant foods. Whoa. Never heard of that, that is quite interesting. I wonder if some people have that sensitivity and not know it.
  - deleted 4y ago
    [deleted]
- aatd86 4y ago
  Interesting. I know that caffeine can induce psychosis and there is also caffeine in both tea and cacao. Got to be careful in consuming some of these foods and supplements (pre workouts etc, fat-burners) in large quantities. https://www.cambridge.org/core/journals/cns-spectrums/article/abs/caffeineinduced-psychosis/2256285A0D03C906380242E1ECCE187B https://www.cambridge.org/core/journals/cns-spectrums/articl...
- stainforth 4y ago
  How did you encounter that you have that genetic sensitivity?
  - FollowingTheDao 4y ago
    Obtained my genetics from 23andme, downloaded the raw data and went to work. Learned nutritional genetics in my spare time.
qclibre22 4y ago
I did notice the "the California Walnuts Commission" funded the study.
- hombre_fatal 4y ago
  Well, it's also sponsored by various government bodies, not that it matters. If there's a problem with the methodology, why not focus on that? Private sponsorship being an automatic conflict of interest that compromises research is a tired trope. All you can do is evaluate the methodology. For all you know, the researchers themselves are motivated reasoners with zero funding.
  - qclibre22 4y ago
    Good point. Good science should independent of funding and politics. Methodology is not that bad for a nutrition study. I am concerned with compliance verification. A "keep doing whatever" group would have been a great control.
porknubbins 4y ago
So the study participants all lost weight but the study claims even controlling for weight loss the green Med diet eaters lost double the visceral adipose tissue. This is an incredible result given that its the first suggestion I’ve ever seen that you could almost redistribute fat in a healthy way without a negative energy balance. This is like all those BS diet adds online saying “lose wheat belly for those over forty” except true?
greggeter 4y ago
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33 points by lxm 4y ago

Very much to do with the Polyphenols inhibiting or increasing Nitric Oxide Synthase. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3524723/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3524723/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2723458/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2723458/ https://academic.oup.com/eurheartj/article/24/13/1210/397048 https://academic.oup.com/eurheartj/article/24/13/1210/397048 Myself, I cannot drink green tea or eat chocolate because it inhibits NOS1 and I have a genetic sensitivity (NOS1AP) that causes them to trigger mania, anxiety, and insomnia as do many of the phenols in many plant foods. https://onlinelibrary.wiley.com/doi/10.1111/gbb.12193 https://onlinelibrary.wiley.com/doi/10.1111/gbb.12193

readingnews 4y ago
>> Myself, I cannot drink green tea or eat chocolate because it inhibits NOS1 and I have a genetic sensitivity (NOS1AP) that causes them to trigger mania, anxiety, and insomnia as do many of the phenols in many plant foods. Whoa. Never heard of that, that is quite interesting. I wonder if some people have that sensitivity and not know it.
- deleted 4y ago
  [deleted]
aatd86 4y ago
Interesting. I know that caffeine can induce psychosis and there is also caffeine in both tea and cacao. Got to be careful in consuming some of these foods and supplements (pre workouts etc, fat-burners) in large quantities. https://www.cambridge.org/core/journals/cns-spectrums/article/abs/caffeineinduced-psychosis/2256285A0D03C906380242E1ECCE187B https://www.cambridge.org/core/journals/cns-spectrums/articl...
stainforth 4y ago
How did you encounter that you have that genetic sensitivity?
- FollowingTheDao 4y ago
  Obtained my genetics from 23andme, downloaded the raw data and went to work. Learned nutritional genetics in my spare time.

qclibre22 4y ago

I did notice the "the California Walnuts Commission" funded the study.

hombre_fatal 4y ago
Well, it's also sponsored by various government bodies, not that it matters. If there's a problem with the methodology, why not focus on that? Private sponsorship being an automatic conflict of interest that compromises research is a tired trope. All you can do is evaluate the methodology. For all you know, the researchers themselves are motivated reasoners with zero funding.
- qclibre22 4y ago
  Good point. Good science should independent of funding and politics. Methodology is not that bad for a nutrition study. I am concerned with compliance verification. A "keep doing whatever" group would have been a great control.

porknubbins 4y ago

So the study participants all lost weight but the study claims even controlling for weight loss the green Med diet eaters lost double the visceral adipose tissue. This is an incredible result given that its the first suggestion I’ve ever seen that you could almost redistribute fat in a healthy way without a negative energy balance. This is like all those BS diet adds online saying “lose wheat belly for those over forty” except true?

greggeter 4y ago

[dead]