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I'm not a virologist, and this is taxing to my memory, so it will be a bit more basic than you might prefer, and won't be as accurate. > Could it be that reque
by anonymouskimmer 4y ago
I'm not a virologist, and this is taxing to my memory, so it will be a bit more basic than you might prefer, and won't be as accurate.
> Could it be that requesting that the cells produce additional proteins of a particular kind "overloads" them or simply "asks too much" in a fashion similar to a virus?
It could be. I believe that most of the cells that express from the mRNA vaccine do indeed die (from the immune response against them). I'm not positive about this though. In general if a cell is preferentially producing protein from a particular mRNA it doesn't have to resources left to do what is expected of it (including cellular maintenance).
> then what is causing cells to explode due to virus replication?
https://bio.libretexts.org/Bookshelves/Introductory_and_General_Biology/Book%3A_General_Biology_(Boundless)/21%3A_Viruses/21.02%3A_Virus_Infections_and_Hosts/21.2A%3A_Steps_of_Virus_Infections https://bio.libretexts.org/Bookshelves/Introductory_and_Gene...
"During release, the newly-created viruses are released from the host cell, either by causing the cell to break apart, waiting for the cell to die, or by budding off through the cell membrane."
According to the video below it can be caused by crowding. I think it can also be caused by virus proteins, or an apoptotic response - programmed cell death done to hinder the viruses ability to replicate more infectious particles. Often enough the cell does not burst, but simply buds off new virus. This is still very detrimental because the cell isn't doing what it is supposed to do, instead having been hijacked to create new viruses.
> If so, have we encountered a virus that "opens up" a cell without damaging it and eventually becomes parasitic to the host?
What I'm going to say won't directly answer your question, but it will answer the question you would have had if you knew a bit more. You want to look up lytic versus lysogenic viral replication. A basic overview: https://www.khanacademy.org/science/high-school-biology/hs-human-body-systems/hs-the-immune-system/v/viral-replicaiton-lytic-vs-lysogenic https://www.khanacademy.org/science/high-school-biology/hs-h...
A more general overview of viruses linking directly to the part talking about retroviruses (the most common route of viral lysogens in animals): https://bio.libretexts.org/Courses/Mansfield_University_of_Pennsylvania/BSC_3271%3A_Microbiology_for_Health_Sciences_Sp21_(Kagle)/03%3A_Viruses/3.01%3A_Viral_Replication/3.1.02%3A_The_Viral_Life_Cycle#Retroviruses https://bio.libretexts.org/Courses/Mansfield_University_of_P...
- PartiallyTyped 4y agoThank you for the detailed response and the links! Hope you have a great weekend!