3 ms·
There's been a few attempts, but they haven't proven to be effective, e.g. https://www.nature.com/articles/d41591-022-00106-z https://www.nature.com/articles/d4
by Twirrim 4y ago
There's been a few attempts, but they haven't proven to be effective, e.g. https://www.nature.com/articles/d41591-022-00106-z https://www.nature.com/articles/d41591-022-00106-z
- coredog64 4y agoChina has been rolling one out in addition to Sinovax.
- superkuh 4y agoThere have been many attempts. And many of them have proven successful at the ~42 person trial level that failed in this particular study with a common adenovirus as the DNA delivery agent. The one I linked did work in large scale clinical trials which is why it is now being given to the public. Plus intranasal influenza a vaccines have been around since the 1960s. I alternate getting intramuscular and intranasal influenza vaccines for best protection of myself and others. I'm very hopeful for this full scale intranasal roll out of a proven intranasal vaccine for sars-cov-2. I am seriously considering a trip to India to get it as a booster to my 4x mRNA intramusculars from Moderna and BioNTech(Pfizer). I just wish they'd use nebulizers instead of a simple spray. Simple sprays work for the fluid dynamics scales involved in small animal models but as large humans we need nebulizers to get the most complete upper respiratory protection.