Anticholinergics are associated with an increase of risk of dementia, and diphenhydramine is a pretty strong one, considering its OTC nature. I still use it oc

Anticholinergics are associated with an increase of risk of dementia, and diphenhydramine is a pretty strong one, considering its OTC nature. I still use it occasionally myself, but I agree that it's a good idea not to take on a regular basis. Here's a paper from 2019 that covers this: https://jamanetwork.com/journals/jamainternalmedicine/fullarticle/2736353 https://jamanetwork.com/journals/jamainternalmedicine/fullar...