Several things come to mind. First, you don’t need to remove viral DNA from cells. Just make them over-express HIV and trigger cytotoxic lymphocytes or antibody

Several things come to mind. First, you don’t need to remove viral DNA from cells. Just make them over-express HIV and trigger cytotoxic lymphocytes or antibody-mediated killing. You end up wiping all the infected cells. But then, of course, patient is left with compromised immunity. To solve this, you could make a stem cell transplant from a compatible donor. Alternatively, harvest healthy cells before the treatment and transplant them back after. This is from the top of my had, I’m not an expert in the field.