3 ms·

I read this and I wonder why something like dialysis machines couldn't be adapted to filter the blood, recreating an artificial environment in which to attract

I read this and I wonder why something like dialysis machines couldn't be adapted to filter the blood, recreating an artificial environment in which to attract infected CD4 cells. I read a study from around the time of WW1 because blood banks didnt exists then, which is when MDMA aka Ecstasy was invented (for blood clotting purposes) one experiment drained all the blood from a dog, and replaced it with isotonic saline solution. 24hrs later about half the solution had been replaced with blood cells. There was no comment on what effect it had on other parts of the body, like the brain considering the oxygen carrying capacity of the blood. They dont go into detail about which type of CD4+ T cells, there are different types of these cells. Sodium intake will increase Th17 cells which contributes to a class of diseases called autoimmune like arthritis. Its a bit too vague for my liking, and as cells differentiate into different types of cells, the virus must be present somewhere else yet to be detected. This virus sounds like bacteria going dormant in the body by forming biofilms until conditions are right in order to activate again, a risk with antibiotic use and no phage treatment. In fact I wonder if phages have been used to target other virally infected cells, shall have to look that up. 1ml of seawater contains billions of phages. Neutrophils are the only part of the innate immune system I know of which targets pathogens like bacterial biofilms, viruses & foreign objects. Omega 3 EPA & DHA increase in the neutrophil membrane content to make it more effective at targeting pathogens, the higher content also increases the size of the neutrophil making it possible to target larger pathogens. EPA (and possibly ETA a COX inhibitor) also down regulates the osteoclasts, helping to protect and seal the bones, which is where these bone marrow stem cell derived immune cells come from. Once your bones integrity starts to fail, other (adaptive) immune cells get in and start attacking the bone marrow causing the autoimmune diseases. I've seen studies using 8grams a day of Omega 3's ! Histidine/Carnosine would also compliment Omega-3 intake. Now its always been my understanding there are parts of the body CD4 T helper cells cant go, like brain, eyes (eg causing blindness within seconds), testes and ovaries, so to see it mentioned that CD4+ cells are found in the spinal fluid, makes me wonder if there is some sort of blood brain barrier integrity breakdown occurred or is this a Nucleic Acid Amplification Test error, like the type seen with the Covid PCR testing? The CSF is very slow to change as well, it takes weeks and months to get nutrients into CSF compared to other parts of the body. Still interesting none the less.

voldacar 4y ago
How do CD4 T cells cause blindness in seconds if they get into the eye? Here's a study that shows that they could cause inflammation and dryness of the eye, but blindness in seconds? https://pubmed.ncbi.nlm.nih.gov/19339740/ https://pubmed.ncbi.nlm.nih.gov/19339740/
- moremetadata 4y ago
  That's the surface of the eye not inside the eye. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2948372/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2948372/ "The eye attempts to limit local immune and inflammatory responses to preserve vision. This phenomenon, known as ocular immune privilege, is mediated by a combination of local and systemic mechanisms. While immune privilege is believed to protect the eye from day-to-day inflammatory insults, it is not absolute and its mechanisms are still incompletely understood."
  - voldacar 4y ago
    Very interesting, thanks.
ycombinete 4y ago
> I wonder why something like dialysis machines couldn't be adapted to filter the blood I had a similar thought when I was younger. My idea was to just cool the below the temperature that HIV can survive at. When one considers the ways you can contract the disease though (semen, breast milk, blood), it's clear that it's permeated throughout more than just the blood. So just clearing it from the blood would be insufficient to remove the virus from our system.
- moremetadata 4y ago
  True, but it could be an alternative to the ART treatment. The ART treatment also gives away intelligence, namely a theory, which appears to be that reducing viral load to dormancy levels is a valid attack vectory. Likewise the side effects are considered acceptable in much the way someone might consider office rental costs as a cost of business. Such a machine could be an alternative way to reduce those side effect costs, plus there may also be additional benefits from this approach, like rejuvenating the blood or cleaning it. If someone with HIV or any other virus, lived in a sterile environment, so their complete immune system isnt having to tackle other issues, how much would the viral load go down by? Sterile conditions must be important because of the changes COVID has forced on the medical profession, much like HIV also forced surgeons to start wearing latex gloves to reduce infections. I've noticed over the last 4-5 years, AI cancer cell recognition increasingly being adapted for other uses, like counting bacterial biofilms in tissue samples. Would it be possible to visually recognise virally infected cells using AI, by using some sort of adapted dialysis machine? Has anyone even attempted to visually compare good cells against virally infected cells? Such a device could drastically increase some blood cell tests as such a machine could be seen as a realtime blood test lab on wheels, so the cost of setting up and running lab to carryout a variety of blood tests could become something miniturised and mobile. I'm sure the US military and others would invest substantially in that in order to get closer to their super soldier dreams. Even Nasa might be interested in such an idea for the international space station, when thinking of the radiation risks. I've see Breast Cancer detecting AI's get so good now, they can differentiate between a cancer lump and a calcium lump. To the end user, they just a detect a lump which might then trigger a clinical visit, plenty of worry but the clinicians ignore diet which should start showing up statistically along with other meta data obtained from devices like smart watches, supermarket loyalty cards etc etc. These conditions dont happen on their own in isolation, other events have to occur besides the obvious act, like some illicit drug use.

voldacar 4y ago

How do CD4 T cells cause blindness in seconds if they get into the eye? Here's a study that shows that they could cause inflammation and dryness of the eye, but blindness in seconds? https://pubmed.ncbi.nlm.nih.gov/19339740/ https://pubmed.ncbi.nlm.nih.gov/19339740/

moremetadata 4y ago
That's the surface of the eye not inside the eye. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2948372/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2948372/ "The eye attempts to limit local immune and inflammatory responses to preserve vision. This phenomenon, known as ocular immune privilege, is mediated by a combination of local and systemic mechanisms. While immune privilege is believed to protect the eye from day-to-day inflammatory insults, it is not absolute and its mechanisms are still incompletely understood."
- voldacar 4y ago
  Very interesting, thanks.

ycombinete 4y ago

> I wonder why something like dialysis machines couldn't be adapted to filter the blood I had a similar thought when I was younger. My idea was to just cool the below the temperature that HIV can survive at. When one considers the ways you can contract the disease though (semen, breast milk, blood), it's clear that it's permeated throughout more than just the blood. So just clearing it from the blood would be insufficient to remove the virus from our system.

moremetadata 4y ago
True, but it could be an alternative to the ART treatment. The ART treatment also gives away intelligence, namely a theory, which appears to be that reducing viral load to dormancy levels is a valid attack vectory. Likewise the side effects are considered acceptable in much the way someone might consider office rental costs as a cost of business. Such a machine could be an alternative way to reduce those side effect costs, plus there may also be additional benefits from this approach, like rejuvenating the blood or cleaning it. If someone with HIV or any other virus, lived in a sterile environment, so their complete immune system isnt having to tackle other issues, how much would the viral load go down by? Sterile conditions must be important because of the changes COVID has forced on the medical profession, much like HIV also forced surgeons to start wearing latex gloves to reduce infections. I've noticed over the last 4-5 years, AI cancer cell recognition increasingly being adapted for other uses, like counting bacterial biofilms in tissue samples. Would it be possible to visually recognise virally infected cells using AI, by using some sort of adapted dialysis machine? Has anyone even attempted to visually compare good cells against virally infected cells? Such a device could drastically increase some blood cell tests as such a machine could be seen as a realtime blood test lab on wheels, so the cost of setting up and running lab to carryout a variety of blood tests could become something miniturised and mobile. I'm sure the US military and others would invest substantially in that in order to get closer to their super soldier dreams. Even Nasa might be interested in such an idea for the international space station, when thinking of the radiation risks. I've see Breast Cancer detecting AI's get so good now, they can differentiate between a cancer lump and a calcium lump. To the end user, they just a detect a lump which might then trigger a clinical visit, plenty of worry but the clinicians ignore diet which should start showing up statistically along with other meta data obtained from devices like smart watches, supermarket loyalty cards etc etc. These conditions dont happen on their own in isolation, other events have to occur besides the obvious act, like some illicit drug use.