3 ms·
Conrad Waddington and his epigenetic landscape (2013)
- svnt 4y agoThe general hilltop marble idea here of what are now called attractor fields and their use in biological development predates Waddington by some decades. Essentially it seems his work is a reapplication of Sewell Wright’s fitness landscapes from the 1920s and 30s to cell differentiation, and I’m not very sure the idea originated with Wright. Waddington would have been aware of Wright’s work.
- j7ake 4y agoLove the concept, but it’s so over used and misused in talks that I now have an aversion towards seeing that famous illustration