The early studies were with Paxlovid in unvaccinated patients, where it worked pretty good. But by now everyone is vaccinated and/or has caught the pestilence s

The early studies were with Paxlovid in unvaccinated patients, where it worked pretty good. But by now everyone is vaccinated and/or has caught the pestilence several times over, and efficacy against severe disease and death is much less clear-cut. It still provides benefit in the elderly, but not in the rest of the population. Pfizer (!) put out a press release bearing the not-good news: https://www.pfizer.com/news/press-release/press-release-detail/pfizer-reports-additional-data-paxlovidtm-supporting#:~:text=Additional%20analyses%20of%20secondary%20endpoint,placebo%20(p%3D0.0228) https://www.pfizer.com/news/press-release/press-release-deta...