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Probiotic blocks staph bacteria from colonizing people
- DantesKite 4y agoB. subtilis is commonly used to make natto from soybeans as well, giving it sticky, weblike strands, in case anyone was interested in getting more of the probiotic.
- CommanderData 4y agoAlso contains the highest amount of Vitamin K2, good for bone health.
- reducesuffering 4y agoSpecifically, the MK7 form, the best kind (more bioavailable for your bones compared to MK4)
- nielsbot 4y agoOnly problem: You must enjoy natto.
- zoklet-enjoyer 4y agoI never heard of natto, which is kind of surprising considering I've been vegan for most of my life. This seems like the type of thing that vegans would be into. Anyway, looks disgusting and NSFW
- lll-o-lll 4y agoLooks like a bowl of snot. I so have to make this for my kids!
- peatmoss 4y agoIt's very much an acquired taste for most people. I wouldn't say I love it, but am mildly positive towards it.
- beagle3 4y agoIt smells like dirty wet socks you’ve forgotten to wash too. But it tastes ok, even … nice? It’s an acquired taste for sure.
- astrange 4y agoThe natto you get from US Japanese groceries doesn't smell like anything to me. I've always wondered if it's me or them who's wrong considering how people usually complain about it. It does have an unpleasant texture, but the taste is ok if you add the mustard pack.
- oakwhiz 4y agoIt's a different strain though. The strains differ so much that it's difficult to assume that they function the same way.
- doctor_eval 4y agoNatto. It’s sort of like the Japanese version of Vegemite. People who grow up with it, eat it for breakfast. Everyone else in the world thinks you are insane.
- LinuxBender 4y agoI take it in supplement form. A few different formulas actually. That mitigates any taste.
- jo6gwb 4y agoThis seems to be commonly available in many over-the-counter daily probiotic pills and gummies.
- sammalloy 4y agoI met someone with Crohn's disease who swears by the lactic acid bacteria in sour cream to help relieve their symptoms. Apparently it is only certain brands, as the probiotic is added back in after pasteurization.
- NegativeLatency 4y agoWhat brands/products?
- sammalloy 4y agoThe only one I know about is Nancy’s, but I think there’s a few of them. The key is to look for "live probiotics" on the label.
- jMyles 4y agoAnecdotally, I agree that Nancy's sits different in the stomach (in a good way, in moderation). I like it after at least a couple weeks in the fridge.
- L_Rahman 4y agoit's probably l reuterii https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5917019/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5917019/
- eigenrick 4y agoI'm a bit concerned that they don't mention a particular strain of B. Subtilis. There are hundreds of documented strains, and they don't all eat/produce the same things (at least not in the same ratios) Some have been documented to reduce inflammation and restore tight-junction function in epithelial walls (where other strains did not). Others have been shown to reverse the accumulation of α-synuclein. That has been implicated as a cause or symptom of Parkinson's disease.
- jtbayly 4y agoAre you saying that some are good and some are bad strains?
- zabzonk 4y agolike many, many bacteria, b.subtilis can infect you in bad ways, particularly if you are immune-compromised. in general, it is probably not a good idea to mess with your body's microfauna, which normally balances itself, unless you have a patent infection, in which case you want antibiotics.
- lepus 4y agoThe reference paper says it's MB40: https://pubmed.ncbi.nlm.nih.gov/36646104/ https://pubmed.ncbi.nlm.nih.gov/36646104/
- abadger9 4y agoThat's crazy, I was actually diagnosed with this about 3 days ago - it's living on my skin and I went to the doctor because an area of my skin was visibly red and smelling "fleshy" according to the doctor. Currently on antibiotics that I wasn't too fond of taking but after seeing this, will probably be more aggressive with it.
- ZhadruOmjar 4y agoPlease take Staph seriously, it will kill you if you let it. Keep a track of where your skin is red and if it spreads a lot you should go to a hospital and get IV antibiotics. Your doctor can help with all of this but the short of it is, take it seriously.
- abadger9 4y agoThanks, I am - after reading this article also ordered "Jarrow Formulas" probiotic with this MB40 strain.
- hammock 4y agoLink?
- chasil 4y agoThis medpagetoday article implies that the supplement from SuperSmart was used (from the photo). I don't see specific mention of MB40 on the packaging, but Walmart sells this for under $20. https://www.medpagetoday.com/infectiousdisease/generalinfectiousdisease/102709 https://www.medpagetoday.com/infectiousdisease/generalinfect... For $16, I'll gamble that it will help. https://us.supersmart.com/en/shop/immune-system/bacillus-subtilis-supplement-0700 https://us.supersmart.com/en/shop/immune-system/bacillus-sub...
- acchow 4y agoMedPageToday just looked up any product with B. subtilis in it. There is no reason to believe that the study used this brand, or that this product contains the strain under study.
- ZhadruOmjar 4y agoHuge news if this turns out to be something that people can take over the counter to prevent staph. I've shared this with some jiu jitsu friends and hopefully its true and could bring down the rate of infections at gyms.
- zabzonk 4y agoto be honest, i never knew that staph could colonise the gut, to any great extent. certainly, back when i was a medical microbiologist, we never looked for them there, and we never saw any problems with it there. generally, staph is a commensal on skin and other surface tissues. you will never get rid of it there. problems come when it makes its way into things like surgical wounds.
- jimmySixDOF 4y agoI am still upset uBiome turned out to be up there with FTX and Theranos. I had a a small sample set going and would have been super interested to have that over decades or spot check what this MB40 looks like after 6month in me in particular. Seems like such a need for citizen science to generate enough data to look for patterns across populations of both us and the mirobio.
- astrange 4y agoThere are other poop-testing labs, if poop-testing is what you're after.
- gardenfelder 4y agoTrick is to find a testing lab that doesn't sell probiotics. American Gut Health used to be that lab, but they're too busy sequencing Covid now. Hope they get back into the game.
- throwawaytwit9 4y agoThe MB40 strain appears to be this one: >BIO-CAT, Inc. -- a Virginia-based biotech company specializing in breakthrough enzyme product development -- has announced a global partnership with Kerry, the Taste & Nutrition company and their BIO-CAT Microbials, LLC probiotic products division. Effective June 2021, Kerry will lead the sales, marketing, and distribution of BIO-CAT's proprietary probiotic strain, OPTI-BIOME MB40®. >OPTI-BIOME MB40® (Bacillus subtilis ATCC122264) is a non-GMO, highly-stable probiotic strain that the company says is an ideal ingredient for a wide array of dietary supplements and other related uses. Source: https://www.biospace.com/article/releases/bio-cat-announces-partnership-with-kerry-for-global-distribution-of-opti-biome-mb40-probiotic/ https://www.biospace.com/article/releases/bio-cat-announces-...
- graypegg 4y ago… non-GMO? How do you manage that? Is a culture considered non-GMO as long as you’re just pipetting colonies around and hoping for the them to be stressed the right way to evolve something useful?
- kurthr 4y agoWell, otherwise just about every plant and animal we use in agriculture would be GMO for the last 1000 years.
- ISL 4y agoYep.
- bbojan 4y agoAny organism we bred is genetically modified by definition. That's why "transgenic" is a much more accurate term that we should be using.
- menacingly 4y agoI think this is a failure to recognize the distinction between having modified genetics, and having been genetically modified.
- giantg2 4y agoI wonder were you find these beneficial probiotics/strains naturally.
- refuse 4y agoI listened to a piece on NPR the other day about how they discovered a medieval cure for staph that was very effective. They're still trying to figure out the how and why but it was fascinating. https://radiolab.org/episodes/best-medicine https://radiolab.org/episodes/best-medicine
- jMyles 4y ago> I listened to a piece on NPR Friendly correction: Radiolab is a production of (my former client) WNYC, not NPR. My sense is that the creative freedom and energy at WNYC is substantially different than in the NPR editorial process.
- liamdgray 4y agoThank you for explaining. But also: Many NPR stations air Radiolab, and that is where I, and probably GP, hear it.
- jMyles 4y agoWhat I'm suggesting is that we step back from referring to our public radio stations - even NPR member and associate stations - as "NPR stations" (with perhaps exceptions for the regional bureaus and arguably WAMU) and instead think of them as a decentralized network of content production. If you are listening to Radiolab on KQED or WBUR, then NPR had little to do with it (and, I argue, it shows! In a good way!). Many local public radio stations are member stations of both NPR and PRX, but we never hear people call them "PRX stations". Why? I think the answer is almost certainly because the NPR and CPB fact sheets and on-air station identifications refer to them that way. But nearly all of the best programs that are distributed to our local public radio stations are actually being ground out by energetic, lesser-known producers and journalists at much smaller local radio stations, with which they identify much more strongly than they identify with a particular syndicator. If you like Radiolab, understand how the unique culture at WNYC creates a show like that, and consider that your esteem for public radio may be more nuanced than NPR.
- gumby 4y agoI really worried about this on a hospitalization earlier this year when I was given so much antibiotic that my gut was seemingly completely reset to the null state.* That is, I was quite worried that something unpleasant would take it as an invitation to colonize my gut instead, so I ate a LOT of live culture yoghurt. Quite unpleasant when you can't digest anything properly (I'll spare the details) but I rapidly recolonized my gut and restored things to working order. The disturbing sequela was that my interest in certain foods after this process was quite different from my interest before I was sick. It makes me wonder if I ever wanted a donut (or coffee) or if it was some other species signalling to my brain that I wanted to eat such a thing. Nowadays I have little interest in such things. * surely not reset completely to 0. And while I didn't want that to happen I am super glad I got those antibiotics!
- captainkrtek 4y agoThat’s an interesting experience, and I’m glad it worked out for you! I had a really bad infection for a couple weeks after some food poisoning, in and out of the hospital. After that point and recovering with lingering effects for a couple years, my diet changed quite a bit as well. Not sure if for similar reasons, but gravitated away from previous foods/habits.
- jonplackett 4y agoAnyone know somewhere you can buy the strain mentioned (OPTI-BIOME MB40 Bacillus subtilis) in the UK?
- techwiz137 4y agoThis is right up my alley, for me. I have been suffering from a staph infection on the scalp for the last decade. I am colonized, and every time I do a cycle on Doxycycline I am clean for 4-5 days and it's back... The symptoms are puss filled boils on the head, sometimes bloody. Sometimes known as folliculitis. I believe I am colonized, but I also believe my cat is also infected and we mutually retransmit it to each other as we share pillows. It all started in the nose 10 years ago, unlocked all sorts of issues and permanently damaged it. Then it spread to the scalp. It seriously reduced my QoL and made visits to a barber a challenge. It increased my hair shedding aka more prone to balding.
- batter 4y agoSilly question, but do you supplement Zinc? I've had something similar in yong age. I think it was fixed by Immune globulin injection. Yeah, I know it's strange, but for some reason it worked. Lately I've noticed that this stuff can come back if my immune system depressed. Sleep + Zinc usually helps.
- techwiz137 4y agoWell I would say not directly, some of my supplements have Zinc, but that is as far as it went. I and my immediately family, all of suffer from forms of Thalassemia ranging from mild, to severe. I have a form called Beta Thalassemia Minor, if it affects my immune system.
- tonyc123 4y agoPlease does anyone know where to buy this strand? Many of us need to replicate this study. I cannot find this strain for sale by itself. Only a few products with it combine with others and overall a very low dose of the mb40. Study shows 10 billion CFU