4 ms·

IBD (including ulcerative colitis, which increases the risk of colorectal cancer dramatically) is also increasing in developed/westernized countries.[1] It's u

IBD (including ulcerative colitis, which increases the risk of colorectal cancer dramatically) is also increasing in developed/westernized countries.[1] It's unclear how much of this is is due to changes in diet, hygiene hypothesis, or environmental pollutants/endocrine disruptors. I wish we understood this better. [1] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4020403/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4020403/

quartz 4y ago
My family has personally experienced this and it is terrifying to learn how little information and how few resources there are for young children with IBD. Right out of the gate you hit the issue that there simply aren't many "very early onset IBD" (impacting children under 6 years old) specialists because historically there were so few cases. We've seen well regarded IBD specialists who reflexively try to order tests and procedures that their own hospital will then refuse to even perform because they can't be done safely on young children. The IBD specialists are in general simply unfamiliar with young children because of the historical rarity. From the VEO IBD specialists we have worked with they all report that the numbers are exploding and no one has any real idea why. On top of that most of the more modern and effective treatments for IBD and Crohns aren't approved for young children at all and even top tier insurance will fight tooth and nail against covering them because their use in children can be considered off-label.
- latchkey 4y ago
  Chloramine (chlorine and ammonia) in the water we drink has been linked to IBD, IBS and Crohn’s. Most large cities switched to this now in the US (San Francisco switched in 2004). It is also difficult to filter out of water. We shower in it too, vaporized into our lungs with hot water.
  - Fatnino 4y ago
    Why does San Francisco put anything in the water? It has some of the best tap water in the country. Hetch hetchy water exceeds all federal and state criteria for tap or bottled water. Raw.
    - latchkey 4y ago
      I don't get why people think that water is somehow safe because it comes from some magical place. Water still needs to be transported 167 miles from HH, during which it can pick up plenty of things, like lead, chromium 6, bacteria and all sorts of other fun stuff. Never mind it has likely sat in a local reservoir for some period of time and who knows what the condition of those things are. Before it was chlorine and then apparently that wasn't enough, so they switched to chloramine. Then, they do shit like this, with some weird spin on it: https://www.sfgate.com/bayarea/article/SF-s-pure-drinking-water-to-get-a-new-ingredient-10949336.php https://www.sfgate.com/bayarea/article/SF-s-pure-drinking-wa... I had several fish tanks (one ~400 gallons) that I was caring for during that switch over. I tried to do filtration and additives and the fish were never the same, they all died. It just seems intuitive that adding something to water that kills fish almost instantly, couldn't be great for humans either. Needless to say, I only drink RO water, put a filter on my whole house and in my shower. That probably isn't enough, but at least it is better than nothing. https://www.epa.gov/dwreginfo/chloramines-drinking-water https://www.epa.gov/dwreginfo/chloramines-drinking-water https://19january2017snapshot.epa.gov/www3/region9/water/chloramine.html https://19january2017snapshot.epa.gov/www3/region9/water/chl...
      - Fatnino 4y ago
        HH water runs inside pipes almost the whole way. It's not picking up much. Are you drinking local RO water? Like rain off your roof? Isn't that full of local smoke particles?
        bearmode 4y ago
        Maybe reverse osmosis water?
        latchkey 4y ago
        Correct
        latchkey 4y ago
popotamonga 4y ago
I have UC my doctor told me it just slightly increases the chance whereas some years ago they thought it increased a lot. Is she lying to me or what
- faeriechangling 4y ago
  Relative vs absolute risk, relative risk increases sharply but colorectal cancer is (was?) not that common.
kulahan 4y ago
I'm 99% certain it's a new lack of fiber as the American diet becomes more attuned to meat and starch. I would bet MONEY that if you looked at IBD rates among people who tend to frequent taco bell (lots of beans == lots of fiber) and people who tend to frequent, say, McD's, you'd see a lower rate among TB-goers. Doesn't seem like a hard experiment to set up.
- bob1029 4y ago
  > lots of beans == lots of fiber Are we sure Taco Bell has not discovered a novel way to remove important nutrients from this item as well?
  - pacomerh 4y ago
    A bowl of beans at home is not the same as beans from Taco Bell of course.
- gnabgib 4y ago
  Dennis Burkitt documented this in 1973[0][1]. Unfortunately "Don't Forget Fibre in your Diet" (1979) and "F-Plan Diet" (1983) have faded into history a bit. [0]: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1588096/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1588096/ [1]: https://en.wikipedia.org/wiki/Denis_Parsons_Burkitt https://en.wikipedia.org/wiki/Denis_Parsons_Burkitt
- hnzix 4y ago
  Fiber supplementation can worsen symptoms of IBS as it draws water into the colon. "Just eat more fibre" is a knee jerk response of people unfamiliar with the science. These conditions are corelated to inflamation and often it's FODMAPs which are a major contributor.
  - FearlessNebula 4y ago
    This is just wrong. First of all, IBS != IBD. Second of all, IBD doctors will flat out recommend high fiber Mediterranean style diets for anybody who is not in an active flair.

quartz 4y ago

My family has personally experienced this and it is terrifying to learn how little information and how few resources there are for young children with IBD. Right out of the gate you hit the issue that there simply aren't many "very early onset IBD" (impacting children under 6 years old) specialists because historically there were so few cases. We've seen well regarded IBD specialists who reflexively try to order tests and procedures that their own hospital will then refuse to even perform because they can't be done safely on young children. The IBD specialists are in general simply unfamiliar with young children because of the historical rarity. From the VEO IBD specialists we have worked with they all report that the numbers are exploding and no one has any real idea why. On top of that most of the more modern and effective treatments for IBD and Crohns aren't approved for young children at all and even top tier insurance will fight tooth and nail against covering them because their use in children can be considered off-label.

latchkey 4y ago
Chloramine (chlorine and ammonia) in the water we drink has been linked to IBD, IBS and Crohn’s. Most large cities switched to this now in the US (San Francisco switched in 2004). It is also difficult to filter out of water. We shower in it too, vaporized into our lungs with hot water.
- Fatnino 4y ago
  Why does San Francisco put anything in the water? It has some of the best tap water in the country. Hetch hetchy water exceeds all federal and state criteria for tap or bottled water. Raw.
  - latchkey 4y ago
    I don't get why people think that water is somehow safe because it comes from some magical place. Water still needs to be transported 167 miles from HH, during which it can pick up plenty of things, like lead, chromium 6, bacteria and all sorts of other fun stuff. Never mind it has likely sat in a local reservoir for some period of time and who knows what the condition of those things are. Before it was chlorine and then apparently that wasn't enough, so they switched to chloramine. Then, they do shit like this, with some weird spin on it: https://www.sfgate.com/bayarea/article/SF-s-pure-drinking-water-to-get-a-new-ingredient-10949336.php https://www.sfgate.com/bayarea/article/SF-s-pure-drinking-wa... I had several fish tanks (one ~400 gallons) that I was caring for during that switch over. I tried to do filtration and additives and the fish were never the same, they all died. It just seems intuitive that adding something to water that kills fish almost instantly, couldn't be great for humans either. Needless to say, I only drink RO water, put a filter on my whole house and in my shower. That probably isn't enough, but at least it is better than nothing. https://www.epa.gov/dwreginfo/chloramines-drinking-water https://www.epa.gov/dwreginfo/chloramines-drinking-water https://19january2017snapshot.epa.gov/www3/region9/water/chloramine.html https://19january2017snapshot.epa.gov/www3/region9/water/chl...
    - Fatnino 4y ago
      HH water runs inside pipes almost the whole way. It's not picking up much. Are you drinking local RO water? Like rain off your roof? Isn't that full of local smoke particles?
      - bearmode 4y ago
        Maybe reverse osmosis water?
        latchkey 4y ago
        Correct
      - latchkey 4y ago

popotamonga 4y ago

I have UC my doctor told me it just slightly increases the chance whereas some years ago they thought it increased a lot. Is she lying to me or what

faeriechangling 4y ago
Relative vs absolute risk, relative risk increases sharply but colorectal cancer is (was?) not that common.

kulahan 4y ago

I'm 99% certain it's a new lack of fiber as the American diet becomes more attuned to meat and starch. I would bet MONEY that if you looked at IBD rates among people who tend to frequent taco bell (lots of beans == lots of fiber) and people who tend to frequent, say, McD's, you'd see a lower rate among TB-goers. Doesn't seem like a hard experiment to set up.

bob1029 4y ago
> lots of beans == lots of fiber Are we sure Taco Bell has not discovered a novel way to remove important nutrients from this item as well?
- pacomerh 4y ago
  A bowl of beans at home is not the same as beans from Taco Bell of course.
gnabgib 4y ago
Dennis Burkitt documented this in 1973[0][1]. Unfortunately "Don't Forget Fibre in your Diet" (1979) and "F-Plan Diet" (1983) have faded into history a bit. [0]: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1588096/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1588096/ [1]: https://en.wikipedia.org/wiki/Denis_Parsons_Burkitt https://en.wikipedia.org/wiki/Denis_Parsons_Burkitt
hnzix 4y ago
Fiber supplementation can worsen symptoms of IBS as it draws water into the colon. "Just eat more fibre" is a knee jerk response of people unfamiliar with the science. These conditions are corelated to inflamation and often it's FODMAPs which are a major contributor.
- FearlessNebula 4y ago
  This is just wrong. First of all, IBS != IBD. Second of all, IBD doctors will flat out recommend high fiber Mediterranean style diets for anybody who is not in an active flair.