5 ms·

Subjectively (1 of 1), I take 20k IU/day of D3 (and K2/mk7) and feel both happier and healthier, from about a week after I started supplementing. Was very low l

by rdl 4y ago

Subjectively (1 of 1), I take 20k IU/day of D3 (and K2/mk7) and feel both happier and healthier, from about a week after I started supplementing. Was very low levels of vitamin D before, and symptoms of astigmatism, etc., and all of this improved (blood D levels are in the very high range of normal now).

EwanG 4y ago
I'm sorry, but am I reading this correctly that after you started supplementing your Vit D that your astigmatism went away? I have some rather expensive glasses that I didn't think were affected by diet...
- rdl 4y ago
  Yes. My ophthalmologist said it was specifically due to reduced plasticity in the retina, which caused variable astigmatism. He's a top researcher/published on this specific thing. (Obviously this is not the majority of astigmatism causes in the broader world, but was for me. Another interesting cause is parasites in eyelids, treatable with ivermectin, lol.)
  - rdl 4y ago
    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6075645/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6075645/ (Dr. McMillan is probably the best medical doctor of any specialty I've ever interacted with in any context, and I worked in hospitals for years.)
password11 4y ago
20,000 IU/day is a lot of vitamin D, about 20x the RDA for both the U.S. and the UK [1]. Is this safe, and if so would a doctor ever recommend to do this every day? [1]: https://ods.od.nih.gov/factsheets/vitamind-healthprofessional/ https://ods.od.nih.gov/factsheets/vitamind-healthprofessiona...
- CBarkleyU 4y ago
  > Is this safe, Maybe? > and if so would a doctor ever recommend to do this every day? Most definitely not, but then again, Doctors err on the side of caution for obvious reasons
  - Enginerrrd 4y ago
    >Most definitely not, but then again, Doctors err on the side of caution for obvious reasons Let me rephrase this slightly: Doctors err on the side of caution in terms of the liability of performing a medical intervention (Such as advising to take a supplement). There are many cases where the advice from an MD minimizes their liability and risk but doesn't optimize health for the most number of people. It's much harder to sue over a lack of an intervention than it is to sue over an intervention that produced a negative outcome. Both happen for sure, but there's a systemic bias in the process. In general, this is probably a good thing, but it's nuanced.
    - password11 4y ago
      > There are many cases where the advice from an MD minimizes their liability and risk but doesn't optimize health for the most number of people. That may be true in general, but is there any evidence that regularly taking 20,000 IU/day if vitamin D is optimal for health? I see a lot of articles making an affirmative recommendation not to take more than 4,000 IU/day. Ex: https://www.health.harvard.edu/staying-healthy/too-much-vitamin-d-may-harm-bones-not-help https://www.health.harvard.edu/staying-healthy/too-much-vita...
      - Enginerrrd 4y ago
        Oh, I only mean for it to apply in general. With regard to vitamin D, I think there are more people that would benefit from Vitamin D than there are MD's willing to recommend they take it and get the requisite blood work done to confirm appropriate supplementation rate. However, in general, 20,000IU/day every day is quite high and should be done cautiously if at all.
  - 4y ago

by rdl 4y ago

EwanG 4y ago

I'm sorry, but am I reading this correctly that after you started supplementing your Vit D that your astigmatism went away? I have some rather expensive glasses that I didn't think were affected by diet...

rdl 4y ago
Yes. My ophthalmologist said it was specifically due to reduced plasticity in the retina, which caused variable astigmatism. He's a top researcher/published on this specific thing. (Obviously this is not the majority of astigmatism causes in the broader world, but was for me. Another interesting cause is parasites in eyelids, treatable with ivermectin, lol.)
- rdl 4y ago
  https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6075645/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6075645/ (Dr. McMillan is probably the best medical doctor of any specialty I've ever interacted with in any context, and I worked in hospitals for years.)

password11 4y ago

20,000 IU/day is a lot of vitamin D, about 20x the RDA for both the U.S. and the UK [1]. Is this safe, and if so would a doctor ever recommend to do this every day? [1]: https://ods.od.nih.gov/factsheets/vitamind-healthprofessional/ https://ods.od.nih.gov/factsheets/vitamind-healthprofessiona...

CBarkleyU 4y ago
> Is this safe, Maybe? > and if so would a doctor ever recommend to do this every day? Most definitely not, but then again, Doctors err on the side of caution for obvious reasons
- Enginerrrd 4y ago
  >Most definitely not, but then again, Doctors err on the side of caution for obvious reasons Let me rephrase this slightly: Doctors err on the side of caution in terms of the liability of performing a medical intervention (Such as advising to take a supplement). There are many cases where the advice from an MD minimizes their liability and risk but doesn't optimize health for the most number of people. It's much harder to sue over a lack of an intervention than it is to sue over an intervention that produced a negative outcome. Both happen for sure, but there's a systemic bias in the process. In general, this is probably a good thing, but it's nuanced.
  - password11 4y ago
    > There are many cases where the advice from an MD minimizes their liability and risk but doesn't optimize health for the most number of people. That may be true in general, but is there any evidence that regularly taking 20,000 IU/day if vitamin D is optimal for health? I see a lot of articles making an affirmative recommendation not to take more than 4,000 IU/day. Ex: https://www.health.harvard.edu/staying-healthy/too-much-vitamin-d-may-harm-bones-not-help https://www.health.harvard.edu/staying-healthy/too-much-vita...
    - Enginerrrd 4y ago
      Oh, I only mean for it to apply in general. With regard to vitamin D, I think there are more people that would benefit from Vitamin D than there are MD's willing to recommend they take it and get the requisite blood work done to confirm appropriate supplementation rate. However, in general, 20,000IU/day every day is quite high and should be done cautiously if at all.
- 4y ago