Absolutely. It is speculated that the increasing oxygen level caused a mass extinction event: https://en.wikipedia.org/wiki/Great_Oxidation_Event https://en.wik

Absolutely. It is speculated that the increasing oxygen level caused a mass extinction event: https://en.wikipedia.org/wiki/Great_Oxidation_Event https://en.wikipedia.org/wiki/Great_Oxidation_Event Change has winners and losers. Microbes who evolved to thrive in an anaerobic environment suffered, us oxygen breathers gained advantage.