4 ms·

As far as I can tell, the page doesn't mention at all where the Dodo DNA is coming from. They mention chickens and pigeons etc but not Dodo DNA. Maybe I missed

As far as I can tell, the page doesn't mention at all where the Dodo DNA is coming from. They mention chickens and pigeons etc but not Dodo DNA. Maybe I missed something?

advisedwang 4y ago
This paper [1] shows they extracted the mitochondrial DNA from samples from "the UCSC Paleogenomics ab (samples AMNH 612456, OMNH 1764, AMNH 224546, OMNH 1762, AMNH 616460, Zm1, S1B1, OUMNH 1759), the University of Copenhagen (sample ZMUC AVES-105485), the McMaster University Ancient DNA Centre (samples FMNH 47395, FMNH 47396, and FMNH 47397), and Griffith University (sample D3538)". There is also this one: https://oumnh.ox.ac.uk/learn-the-oxford-dodo https://oumnh.ox.ac.uk/learn-the-oxford-dodo [1] https://bmcecolevol.biomedcentral.com/articles/10.1186/s12862-016-0800-3 https://bmcecolevol.biomedcentral.com/articles/10.1186/s1286...
mfld 4y ago
I was wondering that, too. But: > Shapiro said that she had already completed a key first step in the project — fully sequencing the dodo’s genome from ancient DNA — based on genetic material extracted from dodo remains in Denmark. > The next step was to compare the genetic information with the dodo’s closest bird relatives in the pigeon family — the living Nicobar pigeon, and the extinct Rodrigues solitaire, a giant flightless pigeon that once lived on an island close to Mauritius. It’s a process which would allow them to narrow down which mutations in the genome “make a dodo a dodo,” Shapiro said. (https://edition.cnn.com/2023/01/31/world/dodo-bring-back-from-extinction-colossal-scn/index.html https://edition.cnn.com/2023/01/31/world/dodo-bring-back-fro...) From a technology perspective - due to recent advancements in ancient genome sequencing and synthetic biology methods - I find it's a good time to start such a project. Also note that lots of avian genomes have been sequenced in the last years.

As far as I can tell, the page doesn't mention at all where the Dodo DNA is coming from. They mention chickens and pigeons etc but not Dodo DNA. Maybe I missed something?

advisedwang 4y ago

This paper [1] shows they extracted the mitochondrial DNA from samples from "the UCSC Paleogenomics ab (samples AMNH 612456, OMNH 1764, AMNH 224546, OMNH 1762, AMNH 616460, Zm1, S1B1, OUMNH 1759), the University of Copenhagen (sample ZMUC AVES-105485), the McMaster University Ancient DNA Centre (samples FMNH 47395, FMNH 47396, and FMNH 47397), and Griffith University (sample D3538)". There is also this one: https://oumnh.ox.ac.uk/learn-the-oxford-dodo https://oumnh.ox.ac.uk/learn-the-oxford-dodo [1] https://bmcecolevol.biomedcentral.com/articles/10.1186/s12862-016-0800-3 https://bmcecolevol.biomedcentral.com/articles/10.1186/s1286...

mfld 4y ago

I was wondering that, too. But: > Shapiro said that she had already completed a key first step in the project — fully sequencing the dodo’s genome from ancient DNA — based on genetic material extracted from dodo remains in Denmark. > The next step was to compare the genetic information with the dodo’s closest bird relatives in the pigeon family — the living Nicobar pigeon, and the extinct Rodrigues solitaire, a giant flightless pigeon that once lived on an island close to Mauritius. It’s a process which would allow them to narrow down which mutations in the genome “make a dodo a dodo,” Shapiro said. (https://edition.cnn.com/2023/01/31/world/dodo-bring-back-from-extinction-colossal-scn/index.html https://edition.cnn.com/2023/01/31/world/dodo-bring-back-fro...) From a technology perspective - due to recent advancements in ancient genome sequencing and synthetic biology methods - I find it's a good time to start such a project. Also note that lots of avian genomes have been sequenced in the last years.