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Source on Serotonin not being linked to depression? Serotonin is linked to depression. The illness isn't caused by low serotonin levels, but there are lots of
by whats_a_quasar 4y ago
Source on Serotonin not being linked to depression?
Serotonin is linked to depression. The illness isn't caused by low serotonin levels, but there are lots of brain chemistry things going on in people with depression, some of which involve serotonin. It doesn't require Serotonin to be low initially for raising its level to treat depression. SSRIs do help for many depressed people, myself included.
Elevated Brain Serotonin Turnover in Patients With Depression:
https://jamanetwork.com/journals/jamapsychiatry/fullarticle/482548 https://jamanetwork.com/journals/jamapsychiatry/fullarticle/...
Low receptor levels and low mood:
https://source.wustl.edu/2004/05/low-receptor-levels-and-low-mood/ https://source.wustl.edu/2004/05/low-receptor-levels-and-low...
Depressed monkeys have elevated levels of serotonin in the part of the brain and decreased levels of serotonin in the hippocampus
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4274982/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4274982/
- whats_a_quasar 4y agoRelated Slate Star Codex posts: SSRIS: Much more than you wanted to know: https://slatestarcodex.com/2014/07/07/ssris-much-more-than-you-wanted-to-know/ https://slatestarcodex.com/2014/07/07/ssris-much-more-than-y... Chemical Imbalance: https://slatestarcodex.com/2015/04/05/chemical-imbalance/ https://slatestarcodex.com/2015/04/05/chemical-imbalance/ Polemical Imbalance: https://slatestarcodex.com/2015/04/18/polemical-imbalance/ https://slatestarcodex.com/2015/04/18/polemical-imbalance/
- psychphysic 4y agoWhen you think about it, the idea that sertraline tops up serotonin like Castrol tops up 50w-10 is laughable.