6 ms·

It is truly tiring to see all these "linked" articles. It might be interesting but without some more research it is useless and just messes up with 99.9% of pop

It is truly tiring to see all these "linked" articles. It might be interesting but without some more research it is useless and just messes up with 99.9% of population who will read it and wrongly assume sexual activity prevents cancer. I am currently on a big spree trying to fix my diet and sift true information from all those wrong inferences. Turns out, almost everything I have been told and red is a lie based on wrong inferences. Lifetime of avoiding fat... exactly opposite of what I should have been doing...

ponector 4y ago
What are your current diet assumptions? From what I heard, the best way to stay healthy is to follow mediterranean and DASH diets.
- twawaaay 4y ago
  I am currently "researching", learning all this stuff. So I guess take it with lots of caution? Since you asked, this is headlines of most of what I figured out: * Your main goals should be achieving metabolic flexibility, eliminating most of the "bad" stuff (sugars, processed oils, most carbs, etc.), supplying your body with mitochondrial decouplers daily and doing low level aerobic exercise, consistently. * If you feel hungry at any time you are doing something wrong. * If you feel cold due to lower basal metabolic rate at any time you are doing something wrong (most likely restricting calories in an improper way). * Metabolic flexibility means you can can easily get into and out of fasting. You are not driven by hunger and can easily continue your life (work, exercise, etc.) with or without meals, without detriment. This is typically achieved by periods of ample food as well as periods of fasting (calorie restriction is not fasting). On a daily basis you can restrict your eating window to 4-6 hours. On longer scale it is useful to do periodic changes to your diet (for example intermittent fasting with restricted carbs and calories for 2 months, then follow with 2 weeks of higher calories and carbs). * Bad stuff are sugars and almost everything that is highly processed, refined, enriched, etc. Meat from unhealthy, stressed animals. Getting rid of all or almost all carbs is desirable as long as some carbs are in the diet from time to time to exercise your insulin. * Mitochondrial decouplers are substances that cause your mitochondria to waste energy. Wasted energy is heat. For example (I think...) by supplying myself with mitochondrial decouplers I have shifted my temperature comfort level by about 5C. I can now walk, run, sleep, work at about 5C lower that I did before at the same comfort level. What are mitochondrial decouplers -- polyphenols, medium chain triglycerides, caffeine, ketone bodies, etc. * Low intensity training (I started running about 30 minutes daily at conversational pace) causes your body to develop more mitochondria. More mitochondria present better opportunity for the body to waste heat as well as host of other useful adaptations. You don't have to be running -- taking a brisk walk after your last meal of the day is a fantastic way of getting some activity as well as efficiently clearing blood sugar and improving effective insulin sensitivity (insulin sensitivity is your ability to clear blood sugars, exercise does not improve insulin sensitivity directly but helps clear the sugar making it as if insulin was more effective). * Exposing body to cold. You don't need to start getting cold therapies -- if you live in colder climate like me it is enough to just not avoid cold at all cost. I am running daily regardless of weather and I am wearing clothes just enough to get mostly comfortable after say 15 minutes of running in -2C but maybe a little cold at the start. * Consistently good night of sleep is a must. * High stress can cause blood sugar and insulin resistance. Body reacts to stress by releasing sugar (to prepare you for effort). But chronic stress causes chronic blood sugar causes chronic insulin causes you getting fat and unhealthy. * Carbs cause insulin (duh) which causes: ** fat in your fat stores being unavailable to your body as an energy resource, ** when the fat stored in your body is unavailable to your body you will be hungry even in the presence of hundreds of thousands of calories on you (which is crazy if you think about it), ** your brain is built to seek more carbs when you get hungry. * Fats don't make you fat. People on keto diets quit keto when they finish losing weight because they find they are unable to eat so many calories as fats and they consistently undereat or change their diets unwittingly. * If you have to eat carbs, make effort to reduce their impact. Never eat "naked" carbs -- preceding carbs with fats and/or protein can significantly lower glycemic index. Preceding fats with acids deactivates enzymes in your saliva that cause about 40% of carb digestion in your stomach -- effectively lowering glycemic index (sushi has only 40% of glycemic index of same portion of plain rice -- due to rice vinegar added to the sushi rice). Taking a walk right after carb meal helps body clear blood sugar faster (for example 20 minute brisk walk right after a meal can shorten aftereffects of the meal from 5 to 3 hours).
  - dangwhy 4y ago
    This is an awesome list. I listened to an audiobook called "why we get sick" and every known health condition was linked to 'insulin resistance'. I knew eating carbs was bad but it blew my mind. He even linked prostate cancer to insulin resistence. But unfortunately i checked the references the book and the linked papers didn't really support the case. Even after you get prostate cancer, IGF 1 inhibitors don't seem to do much to slow it down( some small sample studies seem inconclusive https://www.nature.com/articles/s41416-020-0774-1 https://www.nature.com/articles/s41416-020-0774-1)
    - twawaaay 4y ago
      As far as I understand there is couple of ways cancers are linked to insulin. Not necessarily insulin resistance but think in terms of things that cause insulin resistance also help cancer grow. For me the most compelling connection is that people who are likely to develop insulin resistance are also people who are very likely to have relatively little autophagy. Autophagy is a process where your body consumes protein that already exists in your organism. It will consume all sorts of stuff and what is really important is that it will break down abnormal protein like protein that got misfolded. Autophagy is promoted when you fast for at least 14-18 hours -- but people who are constantly eating when they don't sleep don't ever reach fasting this long. It is crazy to take a look at how different people look after losing a lot of weight depending on what kind of route they chose. People who lost weight due to intermittent fasting rather than calorie restriction tend too look much better and have much less loose skin. What happens is, due to IF regime their bodies were regularly undergoing autophagy while they were on IF and during autophay they were essentially "eating" their own protein like unnecessary connective tissue, skin, etc. Without autophagy to periodically clean garbage from your body various unnecessary things just lie there and cause all sorts of mayhem and inflammation. Misfolded protein is potentially carcinogenic because defects in those protein are pretty much random and if a protein gets broken just right it might be causing damage to pretty much anything else. It increases your chance that a random damage can start cancer going somewhere. Another way insulin might be linked to cancer is that insulin is a growth hormone and cancer is a tissue with abnormal growth. I don't know the details and I know enough to say that insulin does not necessarily cause growth of everything (how fun it would be to get your ABS just by overeating...) But it seems really possible that if cancer is sugar-loving tissue that needs lots of it to grow and insulin tells your cells to take as much sugar from bloodstream as they can then cancer might "be loving it". And also there are some cancer treatments that rely on starving or at least slowing cancer growth with a high ketone and low sugar levels.
- menaerus 4y ago
  Basically all Mediterranean dishes are cooked on the olive oil, for which you can find many sources claiming that it is extraordinarily healthy. However, I am starting to be wary of this claim because olive oil has a _lot_ of saturated fats when compared to other food, roughly around 15-16g per 100g. To put this figure into the context: 20% cooking cream, which is usually considered unhealthy because of its high saturated fats ratio, has about the same amount of saturated fats as olive oil, 14-15g per 100g. Saturated fats in butter are exceptionally high, 51g per 100g. What was surprising to me is that even the sunflower oil, an oil which is frowned upon because it's refined, has _less_ of the saturated fats than olive oil, roughly around 13g per 100g. All the rest of the food which we normally consume is in the region of 1-5g per 100g, including the eggs which have 1g of saturated fats per 100g. By knowing for the fact that saturated fats are unhealthy, these stats seem to suggest that olive oil is not as healthy as it is generally considered.
  - haspok 4y ago
    > By knowing for the fact that saturated fats are unhealthy This is simply not true, much less a "fact". This myth most probably comes from the good old American Heart Association who base their opinion of a study way back in the 1960s which was since proven to have been of extremely low quality. There is a ton of info about this online (including scientific studies, not just blog posts), pro and contra, you can read them yourself and then decide who you believe. And butter and olive oil are one of the most healthy foods you can consume in my opinion <= there you have another point of view on the internet :)
    - menaerus 4y ago
      Right, as if the American Heart Association was the only organization in world to examine the effects of saturated fats to our health, and as if the last study on that topic has been done half a century ago. Thanks for your advice but unless you're willing to share that "ton of info" to support your rather absurd claim, I'll stick to my common sense.
      - omniglottal 4y ago
b4je7d7wb 4y ago
Do they not teach you about macronutrients in highschool? I think nutrition is one of the earliest things you figure out that it depends and nobody really knows what their talking about. My mother and wife have a lot of opinions about nutrition that are obviously unscientific, situational and anecdotal. > Lifetime of avoiding fat... exactly opposite of what I should have been doing... There is more nuance involved. What kind of fat? What kind of diet? Calorie surplus? What about salt? What kind of metabolism do you have? It is just impossible to make blanket statements like eat fat, do not eat fat, eat sugar, do not eat sugar. It's your own responsibility to figure it out instead of being told what to do.
- rajamaka 4y ago
  > Do they not teach you about macronutrients in highschool? That's the problem, we were taught this in highschool: https://www.disabled-world.com/pics/1/old-food-pyramid.jpg https://www.disabled-world.com/pics/1/old-food-pyramid.jpg Eat low amounts of natural fat, eat large amount of grain and cereal to be healthy. It was taught to us in a blanket one size fits all methodology
- twawaaay 4y ago
  > It's your own responsibility to figure it out instead of being told what to do. Why bother having education system if you are supposed to figure everything out on your own? How is nutrition different from math or grammar?
  - mrleinad 4y ago
    Because it raises the minimum level for everyone, and even if you're DaVinci, it's good for you that society is not full of cavemen trying to build everything from scratch.
  - JimtheCoder 4y ago
    "How is nutrition different from math or grammar?" Well, because 1 + 1 = 2, all the time, and the optimal diet is different for everyone?
mrleinad 4y ago
Just remember: none of that matters unless you're taking measurements. Make sure to contrast and check whatever you do with regular blood tests that tell you whether you're doing the right thing or needs adjustments because if you continue down that path you're going to fuck yourself up.
- twawaaay 4y ago
  Measurements are useful but stop this BS that whatever you do doesn't matter if you can't measure it. There is a lot of things we can't measure that are worth doing. Like maybe improving your relationship with your wife and kids. Or reducing distraction and improving your focus while you are working. If the only thing you did and mattered in your life was your diet then yes, you would have to keep measuring it obsessively. But I don't want to spend my life focusing on my diet to exclusion of everything else. I have lots of other stuff I want to be doing. A healthy diet for me is one that allows me to not have to monitor and measure and weigh myself constantly. Not measuring is the goal, not the fault of the method.
  - mrleinad 4y ago
    > There is a lot of things we can't measure that are worth doing. Like maybe improving your relationship with your wife and kids And what does that have to do with prostate cancer, I wonder?
- lr1970 4y ago
  > Just remember: none of that matters unless you're taking measurements. Not everything that can be counted counts and not everything that counts can be counted. (attributed to Albert Einstein)
  - mrleinad 4y ago
    As I replied to another person: we're talking about nutrition and prostate cancer. Not about unmeasurable stuff like relationships.
redeux 4y ago
> wrongly assume sexual activity prevents cancer What is the potential danger here? I’m not aware of any links to adverse heath for men ejaculate 21 times or more a month. Are you? Seems low risk for something that will potentially give you a 31% decreased chance to get prostate cancer. >Lifetime of avoiding fat… That’s too bad. Low fat diets have been debunked for at least 20 years. They were pushed by companies that produce high sugar foods. The thing we should actually avoid. I don’t think anyone has the same interest with the topic in the article though.
- twawaaay 4y ago
  > What is the potential danger here? People wasting other peoples time by giving advice that does nothing. Averting focus from things that are productive. Drowning useful information in information that may not necessarily be bad for you but isn't beneficial either.
  - selcuka 4y ago
    > Averting focus from things that are productive. Technically speaking, sex is productive.
    - deleted 4y ago
      [deleted]
    - Too 4y ago
      It’s the attention spent reading disinformation that is meant above.
      - benj111 4y ago
        They were attempting to be humourous. Fairly successfully IMO
        Too 4y ago
        As if this thread needed more already open doors kicked in. Lately feels like this place is turning into Reddit more and more for every day, I’m not only talking about this thread.
wombatpm 4y ago
Makes me wonder about cholesterol. It is used in the brain, but we have had a generation on anti-cholesterol drugs with rising rates of dementia and Alzheimer's

ponector 4y ago

What are your current diet assumptions? From what I heard, the best way to stay healthy is to follow mediterranean and DASH diets.

twawaaay 4y ago
I am currently "researching", learning all this stuff. So I guess take it with lots of caution? Since you asked, this is headlines of most of what I figured out: * Your main goals should be achieving metabolic flexibility, eliminating most of the "bad" stuff (sugars, processed oils, most carbs, etc.), supplying your body with mitochondrial decouplers daily and doing low level aerobic exercise, consistently. * If you feel hungry at any time you are doing something wrong. * If you feel cold due to lower basal metabolic rate at any time you are doing something wrong (most likely restricting calories in an improper way). * Metabolic flexibility means you can can easily get into and out of fasting. You are not driven by hunger and can easily continue your life (work, exercise, etc.) with or without meals, without detriment. This is typically achieved by periods of ample food as well as periods of fasting (calorie restriction is not fasting). On a daily basis you can restrict your eating window to 4-6 hours. On longer scale it is useful to do periodic changes to your diet (for example intermittent fasting with restricted carbs and calories for 2 months, then follow with 2 weeks of higher calories and carbs). * Bad stuff are sugars and almost everything that is highly processed, refined, enriched, etc. Meat from unhealthy, stressed animals. Getting rid of all or almost all carbs is desirable as long as some carbs are in the diet from time to time to exercise your insulin. * Mitochondrial decouplers are substances that cause your mitochondria to waste energy. Wasted energy is heat. For example (I think...) by supplying myself with mitochondrial decouplers I have shifted my temperature comfort level by about 5C. I can now walk, run, sleep, work at about 5C lower that I did before at the same comfort level. What are mitochondrial decouplers -- polyphenols, medium chain triglycerides, caffeine, ketone bodies, etc. * Low intensity training (I started running about 30 minutes daily at conversational pace) causes your body to develop more mitochondria. More mitochondria present better opportunity for the body to waste heat as well as host of other useful adaptations. You don't have to be running -- taking a brisk walk after your last meal of the day is a fantastic way of getting some activity as well as efficiently clearing blood sugar and improving effective insulin sensitivity (insulin sensitivity is your ability to clear blood sugars, exercise does not improve insulin sensitivity directly but helps clear the sugar making it as if insulin was more effective). * Exposing body to cold. You don't need to start getting cold therapies -- if you live in colder climate like me it is enough to just not avoid cold at all cost. I am running daily regardless of weather and I am wearing clothes just enough to get mostly comfortable after say 15 minutes of running in -2C but maybe a little cold at the start. * Consistently good night of sleep is a must. * High stress can cause blood sugar and insulin resistance. Body reacts to stress by releasing sugar (to prepare you for effort). But chronic stress causes chronic blood sugar causes chronic insulin causes you getting fat and unhealthy. * Carbs cause insulin (duh) which causes: ** fat in your fat stores being unavailable to your body as an energy resource, ** when the fat stored in your body is unavailable to your body you will be hungry even in the presence of hundreds of thousands of calories on you (which is crazy if you think about it), ** your brain is built to seek more carbs when you get hungry. * Fats don't make you fat. People on keto diets quit keto when they finish losing weight because they find they are unable to eat so many calories as fats and they consistently undereat or change their diets unwittingly. * If you have to eat carbs, make effort to reduce their impact. Never eat "naked" carbs -- preceding carbs with fats and/or protein can significantly lower glycemic index. Preceding fats with acids deactivates enzymes in your saliva that cause about 40% of carb digestion in your stomach -- effectively lowering glycemic index (sushi has only 40% of glycemic index of same portion of plain rice -- due to rice vinegar added to the sushi rice). Taking a walk right after carb meal helps body clear blood sugar faster (for example 20 minute brisk walk right after a meal can shorten aftereffects of the meal from 5 to 3 hours).
- dangwhy 4y ago
  This is an awesome list. I listened to an audiobook called "why we get sick" and every known health condition was linked to 'insulin resistance'. I knew eating carbs was bad but it blew my mind. He even linked prostate cancer to insulin resistence. But unfortunately i checked the references the book and the linked papers didn't really support the case. Even after you get prostate cancer, IGF 1 inhibitors don't seem to do much to slow it down( some small sample studies seem inconclusive https://www.nature.com/articles/s41416-020-0774-1 https://www.nature.com/articles/s41416-020-0774-1)
  - twawaaay 4y ago
    As far as I understand there is couple of ways cancers are linked to insulin. Not necessarily insulin resistance but think in terms of things that cause insulin resistance also help cancer grow. For me the most compelling connection is that people who are likely to develop insulin resistance are also people who are very likely to have relatively little autophagy. Autophagy is a process where your body consumes protein that already exists in your organism. It will consume all sorts of stuff and what is really important is that it will break down abnormal protein like protein that got misfolded. Autophagy is promoted when you fast for at least 14-18 hours -- but people who are constantly eating when they don't sleep don't ever reach fasting this long. It is crazy to take a look at how different people look after losing a lot of weight depending on what kind of route they chose. People who lost weight due to intermittent fasting rather than calorie restriction tend too look much better and have much less loose skin. What happens is, due to IF regime their bodies were regularly undergoing autophagy while they were on IF and during autophay they were essentially "eating" their own protein like unnecessary connective tissue, skin, etc. Without autophagy to periodically clean garbage from your body various unnecessary things just lie there and cause all sorts of mayhem and inflammation. Misfolded protein is potentially carcinogenic because defects in those protein are pretty much random and if a protein gets broken just right it might be causing damage to pretty much anything else. It increases your chance that a random damage can start cancer going somewhere. Another way insulin might be linked to cancer is that insulin is a growth hormone and cancer is a tissue with abnormal growth. I don't know the details and I know enough to say that insulin does not necessarily cause growth of everything (how fun it would be to get your ABS just by overeating...) But it seems really possible that if cancer is sugar-loving tissue that needs lots of it to grow and insulin tells your cells to take as much sugar from bloodstream as they can then cancer might "be loving it". And also there are some cancer treatments that rely on starving or at least slowing cancer growth with a high ketone and low sugar levels.
menaerus 4y ago
Basically all Mediterranean dishes are cooked on the olive oil, for which you can find many sources claiming that it is extraordinarily healthy. However, I am starting to be wary of this claim because olive oil has a _lot_ of saturated fats when compared to other food, roughly around 15-16g per 100g. To put this figure into the context: 20% cooking cream, which is usually considered unhealthy because of its high saturated fats ratio, has about the same amount of saturated fats as olive oil, 14-15g per 100g. Saturated fats in butter are exceptionally high, 51g per 100g. What was surprising to me is that even the sunflower oil, an oil which is frowned upon because it's refined, has _less_ of the saturated fats than olive oil, roughly around 13g per 100g. All the rest of the food which we normally consume is in the region of 1-5g per 100g, including the eggs which have 1g of saturated fats per 100g. By knowing for the fact that saturated fats are unhealthy, these stats seem to suggest that olive oil is not as healthy as it is generally considered.
- haspok 4y ago
  > By knowing for the fact that saturated fats are unhealthy This is simply not true, much less a "fact". This myth most probably comes from the good old American Heart Association who base their opinion of a study way back in the 1960s which was since proven to have been of extremely low quality. There is a ton of info about this online (including scientific studies, not just blog posts), pro and contra, you can read them yourself and then decide who you believe. And butter and olive oil are one of the most healthy foods you can consume in my opinion <= there you have another point of view on the internet :)
  - menaerus 4y ago
    Right, as if the American Heart Association was the only organization in world to examine the effects of saturated fats to our health, and as if the last study on that topic has been done half a century ago. Thanks for your advice but unless you're willing to share that "ton of info" to support your rather absurd claim, I'll stick to my common sense.
    - omniglottal 4y ago

b4je7d7wb 4y ago

Do they not teach you about macronutrients in highschool? I think nutrition is one of the earliest things you figure out that it depends and nobody really knows what their talking about. My mother and wife have a lot of opinions about nutrition that are obviously unscientific, situational and anecdotal. > Lifetime of avoiding fat... exactly opposite of what I should have been doing... There is more nuance involved. What kind of fat? What kind of diet? Calorie surplus? What about salt? What kind of metabolism do you have? It is just impossible to make blanket statements like eat fat, do not eat fat, eat sugar, do not eat sugar. It's your own responsibility to figure it out instead of being told what to do.

rajamaka 4y ago
> Do they not teach you about macronutrients in highschool? That's the problem, we were taught this in highschool: https://www.disabled-world.com/pics/1/old-food-pyramid.jpg https://www.disabled-world.com/pics/1/old-food-pyramid.jpg Eat low amounts of natural fat, eat large amount of grain and cereal to be healthy. It was taught to us in a blanket one size fits all methodology
twawaaay 4y ago
> It's your own responsibility to figure it out instead of being told what to do. Why bother having education system if you are supposed to figure everything out on your own? How is nutrition different from math or grammar?
- mrleinad 4y ago
  Because it raises the minimum level for everyone, and even if you're DaVinci, it's good for you that society is not full of cavemen trying to build everything from scratch.
- JimtheCoder 4y ago
  "How is nutrition different from math or grammar?" Well, because 1 + 1 = 2, all the time, and the optimal diet is different for everyone?

mrleinad 4y ago

Just remember: none of that matters unless you're taking measurements. Make sure to contrast and check whatever you do with regular blood tests that tell you whether you're doing the right thing or needs adjustments because if you continue down that path you're going to fuck yourself up.

twawaaay 4y ago
Measurements are useful but stop this BS that whatever you do doesn't matter if you can't measure it. There is a lot of things we can't measure that are worth doing. Like maybe improving your relationship with your wife and kids. Or reducing distraction and improving your focus while you are working. If the only thing you did and mattered in your life was your diet then yes, you would have to keep measuring it obsessively. But I don't want to spend my life focusing on my diet to exclusion of everything else. I have lots of other stuff I want to be doing. A healthy diet for me is one that allows me to not have to monitor and measure and weigh myself constantly. Not measuring is the goal, not the fault of the method.
- mrleinad 4y ago
  > There is a lot of things we can't measure that are worth doing. Like maybe improving your relationship with your wife and kids And what does that have to do with prostate cancer, I wonder?
lr1970 4y ago
> Just remember: none of that matters unless you're taking measurements. Not everything that can be counted counts and not everything that counts can be counted. (attributed to Albert Einstein)
- mrleinad 4y ago
  As I replied to another person: we're talking about nutrition and prostate cancer. Not about unmeasurable stuff like relationships.

redeux 4y ago

> wrongly assume sexual activity prevents cancer What is the potential danger here? I’m not aware of any links to adverse heath for men ejaculate 21 times or more a month. Are you? Seems low risk for something that will potentially give you a 31% decreased chance to get prostate cancer. >Lifetime of avoiding fat… That’s too bad. Low fat diets have been debunked for at least 20 years. They were pushed by companies that produce high sugar foods. The thing we should actually avoid. I don’t think anyone has the same interest with the topic in the article though.

twawaaay 4y ago
> What is the potential danger here? People wasting other peoples time by giving advice that does nothing. Averting focus from things that are productive. Drowning useful information in information that may not necessarily be bad for you but isn't beneficial either.
- selcuka 4y ago
  > Averting focus from things that are productive. Technically speaking, sex is productive.
  - deleted 4y ago
    [deleted]
  - Too 4y ago
    It’s the attention spent reading disinformation that is meant above.
    - benj111 4y ago
      They were attempting to be humourous. Fairly successfully IMO
      - Too 4y ago
        As if this thread needed more already open doors kicked in. Lately feels like this place is turning into Reddit more and more for every day, I’m not only talking about this thread.

wombatpm 4y ago

Makes me wonder about cholesterol. It is used in the brain, but we have had a generation on anti-cholesterol drugs with rising rates of dementia and Alzheimer's