4 ms·

The real worry with something like this is that you might knock out a "proofreading gene" on SARS-CoV-2 which currently prevents the virus from mutating very qu

• anonymouskimmer 4y ago
  Interesting twitter thread. I'll just state that sanchak74's statement "2. These mutants are circulating globally now - distinguished by their mutation signatures" is as least partly contradicted by the discussion of the article of this topic (which is also the article that sanchack74 links as supporting that statement). I.e. "At the time of writing we have not identified a molnupiravir-implicated cluster that had spread to more than 21 individuals."
  • atdrummond 4y ago
    As long as those clusters are in far enough apart geographies, I think it is fine to call it a global circulation. Now, to call it “widely” circulating/spread or “openly circulating in the general public” would be another story