Oh, PLCG2! Very interesting. Mutation in this gene arises in some cancer patients when they become resistant to a particular targeted therapy. By sheer happens

Oh, PLCG2! Very interesting. Mutation in this gene arises in some cancer patients when they become resistant to a particular targeted therapy. By sheer happenstance, I am involved with an investigational compound that overcomes PCLG2-driven resistance with a targeted molecule that acts downstream of this woman's activating mutation. I've reached out to see if we can help with a compassionate use protocol for this drug.