I think the general idea is that the biggest ion 2 angstrom tops, more likely 0.2 angstrom, whereas most proteins (where the ion is used) are 30-50 angstroms ac

I think the general idea is that the biggest ion 2 angstrom tops, more likely 0.2 angstrom, whereas most proteins (where the ion is used) are 30-50 angstroms across (and note this is 3d, a 1 angstrom ion is 1000 times smaller than a 10 angstrom protein). And the whole HIV virus particle is ~1200 angstrom across. So that ion is like a mouse compared to a skyscraper.