3 ms·
>TLDR was that it is not patentable so there's no money in it. I think you are overlooking some of the major technical problems with phages. In no particular
by omginternets 4y ago
>TLDR was that it is not patentable so there's no money in it.
I think you are overlooking some of the major technical problems with phages. In no particular order:
1. The immune system develops antibodies for many phages.
2. Microbes develop resistance to phages.
3. Phage multiplication using host cell is a primary step for phage production, and this causes many (serious) adverse effects.
4. Only obligate lytic phages that lyse the bacterial cell directly instead of integrating its genome in bacterial DNA (temperate) are usable for phage therapy. Temperate phages play a major role in the exchange of genetic material between different bacterial strains and often contribute to the pathogenicity.